Alessandro Borgia

St. Jude Children's Research Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index3.4kcitations47works1.72yr avg
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Research Topics

Protein Structure and Dynamics(27), Enzyme Structure and Function(11), Advanced Fluorescence Microscopy Techniques(9), RNA and protein synthesis mechanisms(6), Force Microscopy Techniques and Applications(6)

Publications47 total

BPS2025 - Recovering true FRET efficiencies from smFRET investigations requires triplet state mitigation
Biophysical Journal·2025
BPS2025 - Dissecting the mechanism of aminoglycoside-induced miscoding with spatially multiplexed single-molecule FRET
Biophysical Journal·2025
BPS2025 - Recovering true FRET efficiencies from smFRET investigations requires triplet state mitigation
Biophysical Journal·2025
Recovering true FRET efficiencies from smFRET investigations requires triplet state mitigation
Nature Methods·2024· 10 citedOpen Access
Elucidating the complexation between highly charged disordered proteins with single-molecule FRET (smFRET) and integrative data analysis
Biophysical Journal·2024Open Access
An analytical polymer model to analyze thermodynamics of complexation between highly charged disordered proteins
Biophysical Journal·2024Open Access
Driving forces of the complex formation between highly charged disordered proteins
Proceedings of the National Academy of Sciences·2023· 50 citedOpen Access
Author Correction: Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes
Nature Communications·2023Open Access
Enabling multiperspective single-molecule FRET
Biophysical Journal·2023
Complexes of charged disordered polyelectrolyte-like proteins: From thermodynamics to stuctural plasticity
Biophysical Journal·2023Open Access
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision
Cell·2022· 102 citedOpen Access
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein
Zurich Open Repository and Archive (University of Zurich)·2022· 66 citedOpen Access
Polyelectrolyte complexation of charged IDPs driven by the entropy of counterion release
Biophysical Journal·2022
Molecular Origins of Free Energies Associated with Complex Interactions of Biological Polyelectrolyte-Like Disordered Proteins
Biophysical Journal·2021Open Access
Tuning the Baird Aromatic Triplet State Energy of Cyclooctatetraene to Maximize the Self-Healing Mechanism in Organic Fluorophores
Biophysical Journal·2021Open Access
Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes
Nature Communications·2020· 109 citedOpen Access
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores
Proceedings of the National Academy of Sciences·2020· 63 citedOpen Access
Disordered Proteins Enable Histone Chaperoning on the Nucleosome
2020· 12 citedOpen Access
Thermodynamics of the Interaction between Biological Polyelectrolyte-Like Disordered Proteins: From Binary Complexes to Oligomers
Biophysical Journal·2020· 3 citedOpen Access
Binding without folding – the biomolecular function of disordered polyelectrolyte complexes
Current Opinion in Structural Biology·2019· 100 cited
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Frequent Co-authors

Benjamin Schuler(30), Madeleine B. Borgia(24), Daniel Nettels(22), Robert B. Best(18), Andrea Sottini(11), Jane Clarke(9), Aritra Chowdhury(9), Pétur O. Heidarsson(8), Wenwei Zheng(8), Scott C. Blanchard(8), Andrea Soranno(7), Russ B. Altman(7), Daniel S. Terry(6), Avik Kumar Pati(6), Katrine Bugge(5), Karin Buholzer(5), Birthe B. Kragelund(5), Alexander Grishaev(5), Steffen Jockusch(5), Rohan Eapen(5)