Thomas Clayton

Materials Science · Physical Sciences

20h-index2.0kcitations69works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Enzyme Structure and Function(28), Bacterial Genetics and Biotechnology(14), RNA and protein synthesis mechanisms(11), Protein Degradation and Inhibitors(11), Biochemical and Molecular Research(10)

Publications69 total

Supplementary Table S1 from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Supplementary Table S1 from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Data from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Supplementary Data from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Supplementary Data from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Data from Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
2023Open Access
Escape from Protacs®: Recent Developments in Protein Degradation With Small-Molecule Glues
2021· 1 cited
Abnormal movements and diaphragmatic flutter in a case of suspected induced illness
BMJ Case Reports·2021· 2 citedOpen Access
Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies
Blood Cancer Discovery·2021· 42 citedOpen Access
Profiling CELMoD-Mediated Degradation of Cereblon Neosubstrates
Methods in molecular biology·2021· 4 cited
Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons
ACS Chemical Biology·2020· 41 cited
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells
Blood·2020· 208 citedOpen Access
New Activities of CELMoDs, Cereblon E3 Ligase-modulating Drugs
2020
Cereblon in complex with DDB1, CC-90009, and GSPT1
2020
Crystal structure of the SALL4–pomalidomide–cereblon–DDB1 complex
Nature Structural & Molecular Biology·2020· 97 cited
Structural Basis for Thalidomide Teratogenicity Revealed by the Cereblon-DDB1-SALL4-Pomalidomide Complex
2019
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate
Nature Chemical Biology·2018· 328 cited
Characterization of lysine methyltransferase inhibitors
Acta Crystallographica Section A Foundations and Advances·2017Open Access
P192 Acute Hepatitis C infection: Are we doing enough?: Abstract P192 Table 1
Sexually Transmitted Infections·2016Open Access
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells
Proceedings of the National Academy of Sciences·2015· 55 citedOpen Access
page 1 of 4Next →

Frequent Co-authors

Ian A. Wilson(43), Polat Abdubek(42), Mitchell D. Miller(42), Marc‐André Elsliger(42), Ashley M. Deacon(42), Adam Godzik(42), Scott A. Lesley(42), Lukasz Jaroszewski(41), Heath E. Klock(41), Andrew T. Morse(41), Edward Nigoghossian(41), Ron Reyes(41), Henry van den Bedem(41), Qingping Xu(41), Keith O. Hodgson(41), John Wooley(41), Dennis Carlton(40), Gye Won Han(40), Sanjeev Krishna(39), Tamara Astakhova(39)