François Debaene

Hôpitaux Universitaires de Strasbourg — France

Medicine · Health Sciences

21h-index1.7kcitations53works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Monoclonal and Polyclonal Antibodies Research(13), Hippo pathway signaling and YAP/TAZ(9), Occupational and environmental lung diseases(8), RNA and protein synthesis mechanisms(7), Protein purification and stability(7)

Publications53 total

Deciphering molecular determinants of GPBAR1-Gs protein interactions by HDX-MS and cryo-EM
Scientific Reports·2025Open Access
Deciphering molecular determinants of GPCR-G protein receptor interactions by complementary integrative structural biology methods
2024Open Access
Figure S2 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S2 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S1 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S3 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S4 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Data from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S4 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S3 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Supplementary Methods from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Supplementary Methods from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Figure S1 from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Data from A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
2024Open Access
Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues
SLAS DISCOVERY·2023· 5 citedOpen Access
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
Molecular Cancer Therapeutics·2023· 21 citedOpen Access
The Importance of Charge in Perturbing the Aromatic Glue Stabilizing the Protein–Protein Interface of Homodimeric tRNA-Guanine Transglycosylase
ACS Chemical Biology·2020· 5 citedOpen Access
The importance of charge in perturbing the aromatic glue stabilizing the protein-protein interface of homodimeric tRNA-guanine transglycosylase
2020Open Access
A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
Communications Chemistry·2020· 19 citedOpen Access
Mass Spectrometry‐Based Strategies for Therapeutic Antibodies Extensive Characterization and Optimization (OptimAbs)
2020· 2 cited
page 1 of 3Next →

Frequent Co-authors

Sarah Cianférani(29), Fabrice Ciesielski(12), Hanne Hillen(11), Aurélie Candi(11), Bart Vanderhoydonck(11), Weronika Kowalczyk(11), Leticia Sansores-García(11), Elena C. Kesikiadou(11), Leen Van Huffel(11), Lore Spiessens(11), Marnik Nijs(11), Erik Soons(11), Wanda Haeck(11), Hugo Klaassen(11), Wim Smets(11), Stéphane A. Spieser(11), Arnaud Marchand(11), Patrick Chaltin(11), Lei Chen(11), Adeela Kamal(11)