Nicholas Davies

University of Birmingham — United Kingdom

Medicine · Health Sciences

19h-index1.5kcitations46works2.02yr avg
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Research Topics

Chronic Lymphocytic Leukemia Research(14), DNA Repair Mechanisms(6), Liver physiology and pathology(6), Aldose Reductase and Taurine(6), Lymphoma Diagnosis and Treatment(5)

Publications46 total

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma
Haematologica·2024· 2 citedOpen Access
Correction: Kwok et al. Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives. Cancers 2021, 13, 4681
Cancers·2022Open Access
Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives
Cancers·2021· 20 citedOpen Access
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target
Blood·2021· 30 citedOpen Access
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL
Blood·2019· 27 citedOpen Access
Identification of Novel Therapeutic Targets in Atm-Deficient Lymphomas Using a Whole Genome CRISPR/CAS-9 Screen
Blood·2019
<i>PALB2</i> variant status in hematological malignancies – a potential therapeutic target?
Leukemia & lymphoma/Leukemia and lymphoma·2019· 2 cited
CCDC 1012153: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
BCR Unresponsiveness and 13q14 Duplication Underpin Spontaneous Disease Regression in Chronic Lymphocytic Leukemia
Blood·2017
USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status
Blood·2017· 71 citedOpen Access
Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts
Oncotarget·2017· 16 citedOpen Access
Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein
Oncotarget·2017· 16 citedOpen Access
A New Murine Model for B Cell Malignancies on ATM-Deficient Background Reveals Involvement of Multiple Pathogenic Mechanisms
Blood·2016
A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells
PLoS Computational Biology·2016· 5 citedOpen Access
Malts
Elsevier eBooks·2016· 3 cited
Optimizing Photovoltaic Water Pumping Systems for Developing Countries Through the Addition of a Novel Induced-flow Subsystem
2015· 1 cited
ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells
Blood·2015· 266 cited
BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks
Molecular Cell·2015· 207 cited
Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway
The Lancet·2015· 82 cited
T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice
Disease Models & Mechanisms·2015· 8 citedOpen Access
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Frequent Co-authors

Tatjana Stanković(18), Angelo Agathanggelou(14), Marwan Kwok(11), Ceri Oldreive(11), A. Malcolm R. Taylor(11), Edward Smith(9), Guy Pratt(9), Paul Moss(8), Helen Parry(7), Christopher M. Bunce(7), Grant S. Stewart(6), Philip N. Newsome(6), J.P. Ride(5), Patricia F. Lalor(5), Peter Hillmen(4), Jane Birtwistle(4), Farhat L. Khanim(4), Jingwen Mao(4), Anna Skowrońska(4), Shankara Paneesha(4)