Paul E. Love

Western University — Canada

Immunology and Microbiology · Life Sciences

64h-index15.9kcitations188works5.62yr avg
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Research Topics

T-cell and B-cell Immunology(100), Immune Cell Function and Interaction(97), CAR-T cell therapy research(41), Immunotherapy and Immune Responses(32), Monoclonal and Polyclonal Antibodies Research(17)

Publications187 total

Innate immune-cell-derived BAFF promotes inflammatory response of ICOSL⁺ B cells via non-canonical NF-κB in diabetic autoimmunity
Molecular Therapy·2025
Early events in TCR signaling – the evolving role of ITAMs
Frontiers in Immunology·2025· 4 citedOpen Access
Associations between structural brain measures and cognitive function in bipolar disorder: a systematic review and meta-analysis
Neuropsychopharmacology·2025
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
Cell·2025· 15 cited
Commensal-derived Trehalose Monocorynomycolate Triggers γδ T Cell-driven Protective Ocular Barrier Immunity
2025Open Access
The common murine retroviral integration site activating Hhex marks a distal regulatory enhancer co-opted in human early T-cell precursor leukemia
Journal of Biological Chemistry·2025Open Access
TGF-β-mediated crosstalk between TIGIT+ Tregs and CD226+CD8+ T cells in the progression and remission of type 1 diabetes
Nature Communications·2024· 21 citedOpen Access
Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
Cell Reports·2024· 10 citedOpen Access
Abstract 6324: Antagonism-enforced braking system to enhance CAR T cell therapeutic specificity
Cancer Research·2024
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides
Nature Immunology·2023· 2 citedOpen Access
CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides
Nature Immunology·2023· 26 citedOpen Access
Themis2 regulates natural killer cell memory function and formation
Nature Communications·2023· 12 citedOpen Access
Harnessing TCR/CAR Antagonism to Enhance Immunotherapeutic Precision
Blood·2023
THEMIS increases TCR signaling in CD4 <sup>+</sup> CD8 <sup>+</sup> thymocytes by inhibiting the activity of the tyrosine phosphatase SHP1
Science Signaling·2023· 11 citedOpen Access
TCR/Chimeric Antigen Receptor (CAR) Cross-Antagonism to Fine-Tune CAR-T cell Immunotherapy
The Journal of Immunology·2023Open Access
GRB2 promotes thymocyte positive selection by facilitating THEMIS-mediated inactivation of SHP1
The Journal of Experimental Medicine·2023· 10 citedOpen Access
A Simplified Approach to Evaluating T Cell Development by Flow Cytometry
Methods in molecular biology·2022· 2 cited
Metabolic regulation of T cell development
Frontiers in Immunology·2022· 22 citedOpen Access
THEMIS enhances the magnitude of normal and neuroinflammatory type 1 immune responses by promoting TCR-independent signals
Science Signaling·2022· 12 cited
NuRD complex recruitment to Thpok mediates CD4 <sup>+</sup> T cell lineage differentiation
Science Immunology·2022· 17 citedOpen Access
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Frequent Co-authors

Alexander Grinberg(14), Elizabeth W. Shores(13), Connie L. Sommers(9), LiQi Li(6), Alex Grinberg(5), Lawrence E. Samelson(5), Tom Tran(4), Shoji Uehara(4), Joshua Μ. Farber(4), Sandra M. Hayes(4), Miriam R. Anver(3), Jan B. Dejarnette(3), Chiguang Feng(3), Jan Lee(3), Kun Huang(3), Alfred Singer(3), Heiner Westphal(3), John Drago(2), Warren J. Leonard(2), Hala S. Azzam(2)