Sang M. Lee

Cancer Genetics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index1.2kcitations17works26.72yr avg
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Research Topics

RNA Interference and Gene Delivery(11), Advanced biosensing and bioanalysis techniques(6), Virus-based gene therapy research(6), CRISPR and Genetic Engineering(5), SARS-CoV-2 and COVID-19 Research(2)

Publications17 total

Mannose-Conjugated Cholesterol Containing Lipid Nanoparticles for Active Targeted mRNA Delivery to Liver Sinusoidal Endothelial and Kupffer Cells
Bioconjugate Chemistry·2025· 3 cited
Structure–Activity Relationship of Ionizable Lipids for siRNA and mRNA Lipid Nanoparticle Design
ACS Biomaterials Science & Engineering·2025· 5 cited
Reducing Complexity in Lipid Nanoparticles: Three-Component Zwitterionic Amino Lipids for Targeted Extrahepatic mRNA Delivery
ACS Biomaterials Science & Engineering·2025· 1 citedOpen Access
Dual SORT LNPs for multi-organ base editing
Nature Biotechnology·2025· 15 cited
Efficient Cas9 nuclease-based editing in skeletal muscle via lipid nanoparticle delivery
2025· 2 citedOpen Access
In vivo editing of lung stem cells for durable gene correction in mice
Science·2024· 134 citedOpen Access
In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma
Proceedings of the National Academy of Sciences·2023· 14 citedOpen Access
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
Nature Protocols·2022· 445 citedOpen Access
Lipid Nanoparticle (LNP) Chemistry Can Endow Unique <i>In Vivo</i> RNA Delivery Fates within the Liver That Alter Therapeutic Outcomes in a Cancer Model
Molecular Pharmaceutics·2022· 58 citedOpen Access
Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes
Journal of the American Chemical Society·2021· 156 citedOpen Access
Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration
Pharmaceutics·2021· 19 citedOpen Access
All‐In‐One Dendrimer‐Based Lipid Nanoparticles Enable Precise HDR‐Mediated Gene Editing In Vivo
Advanced Materials·2021· 94 citedOpen Access
A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo
Angewandte Chemie International Edition·2020· 126 citedOpen Access
Lipid‐Modified Aminoglycosides for mRNA Delivery to the Liver
Advanced Healthcare Materials·2020· 40 citedOpen Access
Pharmacokinetics of Tyrosol Metabolites in Rats
Molecules·2016· 26 citedOpen Access
Tetracyclines inhibit activated B cell function
International Immunology·2001· 65 citedOpen Access
pH/Temperature-Sensitive Polymers for Controlled Drug Delivery
2000

Frequent Co-authors

Daniel J. Siegwart(14), Qiang Cheng(8), Shuai Liu(7), Yehui Sun(7), Di Zhang(7), Sumanta Chatterjee(7), Lukas Farbiak(6), Xueliang Yu(5), Tuo Wei(5), Lindsay T. Johnson(5), Xizhen Lian(4), Xu Wang(3), Joshua Robinson(3), Pratima Basak(3), Amogh Vaidya(3), Erick Guerrero(3), Xu Wang(3), Junyu Gong(2), Sean A. Dilliard(2), Minjeong Kim(2)