Germán Leparc

Boehringer Ingelheim (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.5kcitations34works15.32yr avg
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Research Topics

RNA and protein synthesis mechanisms(5), Extracellular vesicles in disease(5), RNA Research and Splicing(4), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(3), Adipose Tissue and Metabolism(3)

Publications34 total

Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1
Journal of Investigative Dermatology·2024· 8 cited
The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
European Journal of Cell Biology·2024· 7 citedOpen Access
Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling
Frontiers in Immunology·2024· 31 citedOpen Access
An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles
Journal of Extracellular Vesicles·2023· 31 citedOpen Access
Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models
Scientific Reports·2022· 23 citedOpen Access
Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells
International Journal of Molecular Sciences·2021· 29 citedOpen Access
Mechanistic model-driven exometabolomic characterisation of human dopaminergic neuronal metabolism
2021· 12 citedOpen Access
In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy
Scientific Reports·2021· 74 citedOpen Access
Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease
Journal of Extracellular Vesicles·2020· 69 citedOpen Access
Gene Expression Profiling in Patients with Idiopathic Pulmonary Fibrosis (IPF) in the INMARK Trial
2020Open Access
Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell‐induced bone pain
Clinical and Experimental Pharmacology and Physiology·2019· 3 cited
DMSO cryopreservation is the method of choice to preserve cells for droplet-based single-cell RNA sequencing
Scientific Reports·2019· 118 citedOpen Access
2309-PUB: The Effect of Linagliptin on the Microbiome of Diabetic ZDF Rats
Diabetes·2019
Exploiting orthology and de novo transcriptome assembly to refine target sequence information
BMC Medical Genomics·2019· 4 citedOpen Access
Peripheral Blood Gene Expression Profiling in the Multicenter IPF-PRO Registry Cohort
2019
BATLAS: Deconvoluting Brown Adipose Tissue
Cell Reports·2018· 130 citedOpen Access
Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice
Genes Brain & Behavior·2018· 86 citedOpen Access
An RNA-Seq atlas of gene expression in mouse and rat normal tissues
Scientific Data·2017· 149 citedOpen Access
738. Evidence from Gene-Environment Mouse Models that Amygdala Oligodendropathy Contributes to Emotional Pathology
Biological Psychiatry·2017
Targeting blood-brain-barrier transcytosis – perspectives for drug delivery
Neuropharmacology·2016· 94 citedOpen Access
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Frequent Co-authors

Tobias Hildebrandt(10), Holger Klein(7), David P. Kreil(5), Elia Stupka(4), Eric J. Simon(4), Florian Gantner(4), Coralie Viollet(4), Bastian Hengerer(4), Birgit Stierstorfer(4), Benjamin Strobel(4), Michael B. Yaffe(3), Francesc Fernández-Albert(3), Christian T. Wohnhaas(3), Patrick Baum(3), Damiano Azzinnari(3), Hannes Sigrist(3), Erich Seifritz(3), Christopher R. Pryce(3), Denis Delić(3), Toshiyuki Obata(2)