Thomas LaFramboise

University School — United States

Medicine · Health Sciences

41h-index8.7kcitations196works0.92yr avg
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Research Topics

Acute Myeloid Leukemia Research(49), Cancer Genomics and Diagnostics(46), Genomic variations and chromosomal abnormalities(20), Epigenetics and DNA Methylation(19), Myeloproliferative Neoplasms: Diagnosis and Treatment(19)

Publications196 total

Invariant patterns of global mutational signatures allow new fundamental insights in etiopathogenesis of bone marrow failure including aplastic anemia and myelodysplasia
Blood·2025Open Access
Novel approaches to identify cellular vulnerabilities in TET2-dependent MDS
Blood·2025Open Access
Telomere content and genomics of myeloid neoplasia by whole-genome sequencing
Blood·2025· 2 citedOpen Access
In vivo multiplexed modeling reveals diverse roles of the TBX2 subfamily and Egr1 in Kras-driven lung adenocarcinoma
Genes & Diseases·2025Open Access
RAPID FIRE SESSION 01
Leukemia Research·2025
Inhibiting 15-PGDH blocks blood–brain barrier deterioration and protects mice from Alzheimer’s disease and traumatic brain injury
Proceedings of the National Academy of Sciences·2025· 5 citedOpen Access
<i>In Vivo</i> Multiplexed Modeling Reveals Diverse Roles of the TBX2 Subfamily and <i>Egr1</i> in <i>Ras</i> -Driven Lung Adenocarcinoma
2025Open Access
Opposing regulation of endoplasmic reticulum retention under stress by ERp44 and PDIA6
Biochemical Journal·2024· 3 citedOpen Access
Identification of Tumor Suppressors and Synthetic Lethal Targets in -7/del7q Myeloid Neoplasms By Iterative Computational Analysis Coupled with Experimental Validation
Blood·2024Open Access
Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors
Blood·2024Open Access
Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia
Blood·2024
PTPN12 Is Targetable and Context-Specific TSG in -7/del7q Myeloid Neoplasia
Blood·2024Open Access
A double Pólya-Gamma data augmentation scheme for a hierarchical Negative Binomial - Binomial data model
Computational Statistics & Data Analysis·2024· 2 citedOpen Access
Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential
Stem Cell Research & Therapy·2023· 10 citedOpen Access
Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets
Leukemia·2023· 20 citedOpen Access
Fig S1 from Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury
2023Open Access
Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
2023Open Access
Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
2023Open Access
Data from Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury
2023Open Access
Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
2023Open Access
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Frequent Co-authors

Jaroslaw P. Maciejewski(10), Matthew Meyerson(8), Sanford D. Markowitz(7), Mikkael A. Sekeres(6), Roman K. Thomas(5), Kwok‐Kin Wong(5), Kinjal Shah(5), William R. Sellers(5), Levi A. Garraway(5), Hideki Makishima(5), Tomas Radivoyevitch(5), Seishi Ogawa(5), Peter C. Scacheri(5), Hassan Awada(5), Babal K. Jha(5), Rameen Beroukhim(4), Heidi Greulich(4), Kenichi Yoshida(4), Yasunobu Nagata(4), Cassandra M. Hirsch(4)