Irina A. Leneva

Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences — Russia

Medicine · Health Sciences

16h-index1.9kcitations61works2.02yr avg
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Research Topics

Influenza Virus Research Studies(32), Respiratory viral infections research(20), interferon and immune responses(6), SARS-CoV-2 and COVID-19 Research(5), Viral Infections and Vectors(5)

Publications61 total

3,3′-Diindolylmethane Improves the Viral Pneumonia Outcomes After Influenza and SARS-CoV-2 Infection in Animal Models
Viruses·2025Open Access
Indole-core inhibitors of influenza a neuraminidase: iterative medicinal chemistry and molecular modeling
European Journal of Medicinal Chemistry·2024· 2 citedOpen Access
The Topical Novel Formulations of Interferon α-2в Effectively Inhibit HSV-1 Keratitis in the Rabbit Eye Model and HSV-2 Genital Herpes in Mice
Viruses·2024· 4 citedOpen Access
Single intranasal immunization with attenuated Wuhan-like SARS-CoV-2 provides highly effective cross-protection against Delta and Omicron VOCs
Research Square (Research Square)·2023· 1 citedOpen Access
Cold-adapted SARS-CoV-2 variants with different temperature sensitivity exhibit an attenuated phenotype and confer protective immunity
Vaccine·2022· 5 citedOpen Access
Inhibition by umifenovir is broadly effective against coronaviruses
2021
Antiviral Activity of Umifenovir In Vitro against a Broad Spectrum of Coronaviruses, Including the Novel SARS-CoV-2 Virus
Viruses·2021· 35 citedOpen Access
CCDC 2098784: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2098785: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens in vitro and in vivo: A Comparative Analysis
Book Publisher International (a part of SCIENCEDOMAIN International)·2021
Optimization of a cellular HBV infection model for use in high-throughput drug screening
Acta Virologica·2021
Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir
Journal of Antimicrobial Chemotherapy·2020· 14 citedOpen Access
Examining protective efficacy of influenza virus NA-containing virus-like particles (VLP) in mouse model of post-influenza bacterial pneumonia caused by Staphylococcus aureus
Russian Journal of Immunology·2020Open Access
Protective efficacy of virus like particles (VLPs) containing the influenza HA and/or NA in a murine model of postinfluenza bacterial pneumonia
2020
Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses
Journal of Medicinal Chemistry·2020· 23 cited
The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens In Vitro and In Vivo
Marine Drugs·2020· 90 citedOpen Access
Antioxidant Potential of Antiviral Drug Umifenovir
Molecules·2020· 53 citedOpen Access
Influenza virus infection and postviral bacterial pneumonia pathogenesis induced by different subtypes of influenza virus in mice
Medical Immunology (Russia)·2020Open Access
Specific Antiviral Activity of Pyrimidinedispirotripiperazinium Alone and in Combination with Acyclovir on a Herpes-Simplex-Virus Infection Model
Pharmaceutical Chemistry Journal·2019· 3 cited
The Potential of Influenza HA-Specific Immunity in Mitigating Lethality of Postinfluenza Pneumococcal Infections
Vaccines·2019· 8 citedOpen Access
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Frequent Co-authors

Irina N. Falynskova(12), Oleg D. Mitkin(12), Andrey A. Ivashchenko(7), Ekaterina A. Glubokova(6), Pavel Yamanushkin(6), Elena A. Govorkova(5), А. А. Поромов(5), I. Т. Fedyakina(5), Т. А. Гуськова(5), Р. Г. Глушков(5), Рубен Карапетян(5), О. А. Свитич(5), А. В. Иващенко(5), Robert G. Webster(4), E. P. Selkova(4), I V Shestakova(4), Н. П. Карташова(4), E. R. Korchevaya(4), Е. Б. Файзулоев(4), Alexandre V. Ivachtchenko(4)