Lena Erlebach

Bernstein Center for Computational Neuroscience Tübingen — Germany

Neuroscience · Life Sciences

6h-index327citations15works6.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(6), Pluripotent Stem Cells Research(4), CRISPR and Genetic Engineering(4), Single-cell and spatial transcriptomics(3), Immune cells in cancer(3)

Publications15 total

Prevention of transgene silencing during human pluripotent stem cell differentiation
Cell stem cell·2026
Comparative lipidomics of iPSC-derived microglia protocols reveal lipid droplet and immune differences mediated by media composition
Stem Cell Reports·2026Open Access
Chimeric organotypic brain slice cultures support the maturation and functional analysis of human iPSC-derived microglia
2025Open Access
Chimeric human organoid and mouse brain slice co-cultures to study microglial function
Cell Reports·2025Open Access
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases
Nature Metabolism·2025· 9 citedOpen Access
Prevention of Transgene Silencing During Human Pluripotent Stem Cell Differentiation
2025· 6 citedOpen Access
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
2024· 19 citedOpen Access
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice
The EMBO Journal·2024· 14 citedOpen Access
Multi‐omic profiling of isogenic ApoE3/3 and ApoE4/4 iPSC‐derived astrocytes uncovers altered lipid metabolism and mitochondrial function of ApoE4 astrocytes
Alzheimer s & Dementia·2023Open Access
Multiomics of iPSC‐derived ApoE3‐ and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism
Alzheimer s & Dementia·2023· 1 citedOpen Access
Understanding the protective effect of the PLCG2 P522R variant in human microglia
Alzheimer s & Dementia·2023Open Access
New in vitro tools to investigate the role of microglia in neurodegeneration
Alzheimer s & Dementia·2023Open Access
A novel miR-99b-5p- <i>Zbp1</i> pathway in microglia contributes to the pathogenesis of schizophrenia
2023Open Access
A reference human induced pluripotent stem cell line for large-scale collaborative studies
Cell stem cell·2022· 265 citedOpen Access
A reference induced pluripotent stem cell line for large-scale collaborative studies
2021· 13 citedOpen Access

Frequent Co-authors

Deborah Kronenberg‐Versteeg(13), Rik van der Kant(8), Martin Kampmann(6), Marc Welzer(5), Leslie M. Thompson(5), Martin Giera(5), Anika Bühler(5), Daniel M. Ramos(4), Indigo V.L. Rose(4), Birgitt Schüle(4), Ernest Arenas(4), Michael E. Ward(4), Florian T. Merkle(4), Femke M. Feringa(4), Damien Olivier‐Jimenez(4), Alessandro Ori‬‬(4), Yassene Mohammed(4), Amanda McQuade(4), William C. Skarnes(3), Ricardo Miramontes(3)