Przemysław Sapieha

Hôpital Maisonneuve-Rosemont — Canada

Medicine · Health Sciences

52h-index9.1kcitations198works11.72yr avg
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Research Topics

Retinal Diseases and Treatments(74), Retinal Development and Disorders(31), Retinopathy of Prematurity Studies(27), Angiogenesis and VEGF in Cancer(23), Axon Guidance and Neuronal Signaling(22)

Publications197 total

Adipocytes influence choroidal neovascularization via PRDM16.
2025
Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy
Nature Communications·2025· 5 citedOpen Access
Hypoxia-inducible factors link poor glycemic control to diabetic retinopathy
Science Translational Medicine·2025
Safety and Efficacy of Senolytic UBX1325 in Diabetic Macular Edema
NEJM Evidence·2025· 10 cited
Corticosteroids reduce pathological angiogenesis yet compromise reparative vascular remodeling in a model of retinopathy
Proceedings of the National Academy of Sciences·2024· 12 citedOpen Access
Multifocal Electroretinography Changes after UBX1325 (Foselutoclax) Treatment in Neovascular Age-Related Macular Degeneration
Journal of Clinical Medicine·2024· 3 citedOpen Access
Corticosteroids prevent pathological angiogenesis yet compromise reparative vascular remodeling in the retina
2024Open Access
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
Nature Medicine·2024· 75 cited
Metabolic Reprogramming of the Neovascular Niche Promotes Regenerative Angiogenesis in Proliferative Retinopathy
2024Open Access
Metabolic Reprogramming of the Neovascular Niche Promotes Regenerative Angiogenesis in Proliferative Retinopathy
2023Open Access
THERAPEUTIC SENOLYSIS IMPROVES VASCULAR FUNCTION DURING DIABETIC RETINOPATHY
Canadian Journal of Diabetes·2023
THERAPEUTIC SENOLYSIS IMPROVES VASCULAR FUNCTION DURING DIABETIC RETINOPATHY
Canadian Journal of Cardiology·2023
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Journal of Neuroinflammation·2023· 10 citedOpen Access
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life
Journal of Clinical Investigation·2023· 28 citedOpen Access
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation
Science·2023· 155 cited
Additional file 2 of HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Figshare·2023Open Access
Additional file 4 of HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Figshare·2023Open Access
Additional file 3 of HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Figshare·2023Open Access
Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis
Proceedings of the National Academy of Sciences·2022· 18 citedOpen Access
The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions
Cells·2022· 14 citedOpen Access
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Frequent Co-authors

Jean‐Sébastien Joyal(14), Andreas Stahl(13), Lois E. H. Smith(13), Florian Sennlaub(13), Sylvain Chemtob(13), Nathan M. Krah(11), Roberta J. Dennison(11), Jing Chen(11), Agnieszka Dejda(10), Molly R. Seaward(9), Flávio Rezende(9), Pierre Hardy(8), Pierre Lachapelle(8), Zhuo Shao(8), Aimee M. Juan(8), Ariel M. Wilson(8), Keirnan Willett(7), Gaëlle Mawambo(7), Frédérick A. Mallette(7), Khalil Miloudi(7)