James W. Fett

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index4.0kcitations53works0.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(20), Glycosylation and Glycoproteins Research(13), Cell Adhesion Molecules Research(12), Cancer, Hypoxia, and Metabolism(11), Monoclonal and Polyclonal Antibodies Research(11)

Publications53 total

479 The discovery and development of potent and specific anti-SialylTn antibodies for the treatment of solid tumors
European Journal of Cancer·2014
The Crystal Structure of Human Angiogenin in Complex with an Antitumor Neutralizing Antibody
Structure·2003· 25 citedOpen Access
A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity
Proceedings of the National Academy of Sciences·2002· 113 citedOpen Access
Inhibition of prostate carcinoma establishment and metastatic growth in mice by an antiangiogenin monoclonal antibody
International Journal of Cancer·2002· 62 cited
Angiogenin
Wiley Encyclopedia of Molecular Medicine·2002
Prevention of human prostate tumor metastasis in athymic mice by antisense targeting of human angiogenin.
PubMed·2001· 63 cited
Novel Antiangiogenic/Cytotoxic Therapies for Advanced Breast Cancer (95 Breast)
Defense Technical Information Center (DTIC)·1999
Regulation of Angiogenin Expression in Human HepG2 Hepatoma Cells by Mediators of the Acute-Phase Response
Biochemical and Biophysical Research Communications·1999· 32 cited
Novel Antiangiogenic/Cytotoxic Therapies for Advanced Breast Cancer.
1998
Chimeric anti-angiogenin antibody cAb 26–2F inhibits the formation of human breast cancer xenografts in athymic mice
Proceedings of the National Academy of Sciences·1998· 44 citedOpen Access
Angiogenin Is Regulatedin Vivoas an Acute Phase Protein
Biochemical and Biophysical Research Communications·1998· 67 cited
Angiogenin Single-Chain Immunofusions:  Influence of Peptide Linkers and Spacers between Fusion Protein Domains
Biochemistry·1996· 74 cited
Angiogenin antagonists prevent tumor growth in vivo.
Proceedings of the National Academy of Sciences·1995· 156 citedOpen Access
A monoclonal antibody to human angiogenin suppresses tumor growth in athymic mice.
PubMed·1994· 97 cited
A Monoclonal Antibody to Human Angiogenin. Inhibition of Ribonucleolytic and Angiogenic Activities and Localization of the Antigenic Epitope
Biochemistry·1994· 47 cited
A cell-surface proteoglycan mediates human adenocarcinoma HT-29 cell adhesion to human angiogenin.
Journal of Biological Chemistry·1994· 55 citedOpen Access
Actin is a surface component of calf pulmonary artery endothelial cells in culture.
Proceedings of the National Academy of Sciences·1993· 62 citedOpen Access
Actin is a binding protein for angiogenin.
Proceedings of the National Academy of Sciences·1993· 132 citedOpen Access
The odyssey of angiogenin: a protein that induces blood vessel growth
Analytical Chemistry·1989· 10 cited
C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin
Biochemical and Biophysical Research Communications·1989· 7 cited
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Frequent Co-authors

Roy R. Lobb(14), Bert L. Vallée(13), Karen A. Olson(11), Daniël J. Strydom(8), Marc E. Key(7), Susanna M. Rybak(7), Edward M. Alderman(6), James Riordan(6), J. L. Bethune(5), Robert Shapiro(5), H.F. Deutsch(4), H. Hugh Fudenberg(4), E M Alderman(3), J. S. Haskill(3), L. A. Radov(3), Thayer C. French(2), J F Riordan(2), Yao Qizhi(2), Sigitas Verselis(2), H. Randolph Byers(2)