Adrian W. Briggs

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index14.7kcitations48works5.02yr avg
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Research Topics

Forensic and Genetic Research(15), Pleistocene-Era Hominins and Archaeology(13), CRISPR and Genetic Engineering(10), Genomics and Phylogenetic Studies(7), T-cell and B-cell Immunology(6)

Publications48 total

An engineered U7 small nuclear RNA scaffold greatly increases ADAR-mediated programmable RNA base editing
Nature Communications·2025· 7 citedOpen Access
A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases <i>in vitro</i> and <i>in vivo</i> ADAR-Mediated Programmable RNA Base Editing
2024· 2 cited
Generative machine learning of ADAR substrates for precise and efficient RNA editing
2024· 5 citedOpen Access
Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity
Frontiers in Immunology·2019· 96 citedOpen Access
Abstract 1541: Directed, unbiased mapping of lentiviral integrations with next generation sequencing in CAR-T cells
Cancer Research·2018· 1 cited
T-cell receptor <i>αβ</i> chain pairing is associated with CD4 <sup>+</sup> and CD8 <sup>+</sup> lineage specification
2018· 7 citedOpen Access
Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire
2017· 31 citedOpen Access
Correction: Corrigendum: Engineering and optimising deaminase fusions for genome editing
Nature Communications·2017· 2 citedOpen Access
Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion
2017· 29 citedOpen Access
Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data
The Journal of Immunology·2017· 174 citedOpen Access
Engineering and optimising deaminase fusions for genome editing
Nature Communications·2016· 75 citedOpen Access
Engineering and optimising deaminase fusions for genome editing
RePEc: Research Papers in Economics·2016Open Access
A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data
The Journal of Immunology·2016· 82 citedOpen Access
Genome Editing With Targeted Deaminases
2016Open Access
Abstract 1442: Comprehensive TIL profiling by simultaneous DNA barcoding of proteins, RNA and natively paired immune receptors from millions of single cells
Cancer Research·2016
Genetic Evidence of Human Adaptation to a Cooked Diet
Genome Biology and Evolution·2016· 39 citedOpen Access
epicPCR (Emulsion, Paired Isolation, and Concatenation PCR)
Protocol Exchange·2015· 3 citedOpen Access
Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing
DSpace@MIT (Massachusetts Institute of Technology)·2015Open Access
Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers
The ISME Journal·2015· 228 citedOpen Access
Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers
DSpace@MIT (Massachusetts Institute of Technology)·2015Open Access
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Frequent Co-authors

Svante Pääbo(17), Johannes Krause(16), Richard E. Green(14), François Vigneault(14), Udo Stenzel(12), Matthias Meyer(12), Tomislav Maričić(11), George M. Church(11), Jeffrey M. Good(8), Janet Kelso(8), Prashant Mali(8), Martin Kircher(6), Kay Prüfer(6), Philip L. Johnson(6), Montgomery Slatkin(6), Stephen J. Goldfless(6), Michael D. Miller(5), Marc Güell(5), John Aach(5), Steven H. Kleinstein(5)