Danna Jennings

Medicine · Health Sciences

46h-index9.6kcitations165works49.52yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(86), Neurological disorders and treatments(64), Autism Spectrum Disorder Research(15), Genetic Neurodegenerative Diseases(14), Botulinum Toxin and Related Neurological Disorders(14)

Publications163 total

A phase I, multi-center, open-label study design to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of DNL952 in adult participants with late-onset Pompe disease
Molecular Genetics and Metabolism·2026
<scp>LRRK2</scp> as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Movement Disorders·2025· 1 cited
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial
Nature Communications·2025· 4 citedOpen Access
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
EBioMedicine·2025· 13 citedOpen Access
<i>LRRK2</i> -associated parkinsonism with and without <i>in vivo</i> evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
Brain Communications·2025· 8 citedOpen Access
Biologically defined neuronal synuclein disease as a tool to advance drug development
npj Parkinson s Disease·2024· 1 citedOpen Access
Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts
npj Parkinson s Disease·2024· 25 citedOpen Access
LRRK2-Associated Parkinsonism With and Without <i>In Vivo</i> Evidence of Alpha-Synuclein Aggregates
2024· 4 citedOpen Access
Biological Staging of the Parkinson’s Progression Markers Initiative (PPMI) Cohort Using the Research Neuronal α-synuclein Disease Integrated Staging System (NSD-ISS) (P11-3.009)
Neurology·2024Open Access
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts
2024· 4 citedOpen Access
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
The Lancet Neurology·2024· 484 citedOpen Access
Decreased Self-reported Physical Fitness Following SARS-CoV-2 Infection and the Impact of Vaccine Boosters in a Cohort Study
Open Forum Infectious Diseases·2023· 6 citedOpen Access
Clinical Characterization of [<sup>18</sup>F]T-008, a Cholesterol 24-Hydroxylase PET Ligand: Dosimetry, Kinetic Modeling, Variability, and Soticlestat Occupancy
Journal of Nuclear Medicine·2023· 4 citedOpen Access
A Biological Definition and Integrated Staging System of Neuronal alpha-Synuclein Disease
Zenodo (CERN European Organization for Nuclear Research)·2023· 2 citedOpen Access
Predictive value of abbreviated olfactory tests in prodromal Parkinson disease
npj Parkinson s Disease·2023· 9 citedOpen Access
<scp>LRRK2</scp> Inhibition by <scp>BIIB122</scp> in Healthy Participants and Patients with Parkinson's Disease
Movement Disorders·2023· 99 citedOpen Access
Serial olfactory testing for the diagnosis of prodromal Parkinson's disease in the PARS study
Parkinsonism & Related Disorders·2022· 11 cited
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
Science Translational Medicine·2022· 233 cited
Serial olfactory testing for the diagnosis of prodromal Parkinson disease in the Parkinson Associated Risk Syndrome (PARS) study (S16.003)
Neurology·2022
Predictive value of UPSIT subsets in prodromal Parkinson disease (P4-11.001)
Neurology·2022
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Frequent Co-authors

Kenneth Marek(30), John Seibyl(24), Andrew Siderowf(22), Caroline M. Tanner(14), Susan Bressman(9), Brit Mollenhauer(8), Lana M. Chahine(8), Steven J. Frucht(8), Joseph H. Friedman(8), Shirley Eberly(8), David Russell(7), Roy N. Alcalay(7), Elise Caccappolo(7), Helen Mejia‐Santana(7), Ming Tang(7), Amy Colcher(7), Martha Nance(7), William K. Scott(7), Cheryl Waters(7), Stanley Fahn(7)