Simon Halegoua

Neuroscience · Life Sciences

36h-index6.1kcitations46works0.02yr avg
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Research Topics

Nerve injury and regeneration(19), Cellular transport and secretion(8), Signaling Pathways in Disease(8), Bacterial Genetics and Biotechnology(7), Protein Kinase Regulation and GTPase Signaling(6)

Publications46 total

A Conserved Function in Phosphatidylinositol Metabolism for Mammalian Vps13 Family Proteins
PLoS ONE·2015· 37 citedOpen Access
Recruitment of Actin Modifiers to TrkA Endosomes Governs Retrograde NGF Signaling and Survival
Cell·2011· 144 citedOpen Access
Trk retrograde signaling requires persistent, Pincher-directed endosomes
Proceedings of the National Academy of Sciences·2010· 66 citedOpen Access
Trk activation in the secretory pathway promotes Golgi fragmentation
Molecular and Cellular Neuroscience·2010· 25 cited
Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling
The Journal of Cell Biology·2010· 91 citedOpen Access
Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones
Journal of Cell Science·2008· 55 citedOpen Access
Trk-signaling endosomes are generated by Rac-dependent macroendocytosis
Proceedings of the National Academy of Sciences·2007· 95 citedOpen Access
Regulation of Ras Signaling Dynamics by Sos-Mediated Positive Feedback
Current Biology·2006· 120 citedOpen Access
Pincher-Mediated Macroendocytosis Underlies Retrograde Signaling by Neurotrophin Receptors
Journal of Neuroscience·2005· 147 citedOpen Access
Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes
The Journal of Cell Biology·2002· 169 citedOpen Access
Sustained Signaling by Phospholipase C-γ Mediates Nerve Growth Factor-Triggered Gene Expression
Molecular and Cellular Biology·2001· 48 citedOpen Access
Fibroblast Growth Factor Receptor 3 Induces Gene Expression Primarily through Ras-independent Signal Transduction Pathways
Journal of Biological Chemistry·2001· 44 citedOpen Access
Identification of the Cytoplasmic Regions of Fibroblast Growth Factor (FGF) Receptor 1 Which Play Important Roles in Induction of Neurite Outgrowth in PC12 Cells by FGF-1
Molecular and Cellular Biology·1998· 66 citedOpen Access
Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons
Proceedings of the National Academy of Sciences·1997· 518 citedOpen Access
Activation of Codependent Transcription Factors Is Required for Transcriptional Induction of the <i>vgf</i> Gene by Nerve Growth Factor and Ras
Molecular and Cellular Biology·1996· 33 citedOpen Access
The Fibroblast Growth Factor Receptor-1 Is Necessary for the Induction of Neurite Outgrowth in PC12 Cells by aFGF
Journal of Neuroscience·1996· 36 citedOpen Access
Calcium influx induces neurite growth through a Src-Ras signaling cassette
Neuron·1995· 258 citedOpen Access
A single pulse of nerve growth factor triggers long-term neuronal excitability through sodium channel gene induction
Neuron·1995· 168 citedOpen Access
Nerve growth factor regulates the abundance and distribution of K+ channels in PC12 cells.
The Journal of Cell Biology·1993· 81 citedOpen Access
Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways
The Journal of Cell Biology·1993· 118 citedOpen Access
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Frequent Co-authors

Gabriella D’Arcangelo(10), Masayori Inouye(9), Polyxeni Philippidou(6), Joan S. Brugge(5), Juan José Toledo‐Aral(5), Wendy Akmentin(5), Gregorio Valdez(5), Sheila Μ. Thomas(4), Gail Mandel(4), Jun Sekizawa(4), Robert C. Armstrong(4), Norbert E. Kremer(3), Michael J. Hayman(3), Akikazu Hirashima(3), S. Rock Levinson(2), H Qi(2), Yufang Shao(2), Julie Rosenbaum(2), J Cremins(2), John A. Wagner(2)