Thomas J Ha

Thermo Fisher Scientific (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index4.6kcitations63works2.02yr avg
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Research Topics

RNA Research and Splicing(11), Medical Imaging Techniques and Applications(9), Medical and Biological Sciences(8), Genomics and Chromatin Dynamics(7), Immunotherapy and Immune Responses(7)

Publications32 total

Analytical and Clinical Validation of the Oncomine Dx Target Test to Assess HER2 Mutation Status in Tumor Tissue Samples From Patients With Non–Small Cell Lung Cancer Treated With Trastuzumab Deruxtecan in the DESTINY-Lung01 and DESTINY-Lung02 Studies
Archives of Pathology & Laboratory Medicine·2024· 4 citedOpen Access
Abstract 7627: First NGS-based companion diagnostic to aid in selecting non-small cell lung cancer patients with <i>ERBB2</i> (HER2) activating mutations for treatment with trastuzumab deruxtecan
Cancer Research·2024
Analytical and clinical validation of oncomine Dx target (ODxT) test and local testing for identifying patients with HER2 (<i>ERBB2</i>)-mutant (HER2m) non–small-cell lung cancer (NSCLC) for treatment with trastuzumab deruxtecan (T-DXd) in DESTINY-Lung01/02 (DL-01/02).
Journal of Clinical Oncology·2023
Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis
BMC Genomics·2019· 30 citedOpen Access
Relationship of <i>MET</i> exon 14 splicing variants and <i>MET</i> exon 14 skipping expression in NSCLC FFPE samples.
Journal of Clinical Oncology·2019· 1 cited
Analytical validation of the Oncomine Pan-Cancer Cell-Free Assay in a CLIA- and CAP-regulated laboratory for detection of solid tumor-derived variants in blood plasma.
Journal of Clinical Oncology·2019· 10 cited
Correction to: Relatively frequent switching of transcription start sites during cerebellar development
BMC Genomics·2018Open Access
Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection
The Cerebellum·2018· 6 cited
FANTOM5 CAGE profiles of human and mouse samples
Scientific Data·2017· 350 citedOpen Access
An integrated expression atlas of miRNAs and their promoters in human and mouse
Nature Biotechnology·2017· 588 citedOpen Access
Relatively frequent switching of transcription start sites during cerebellar development
BMC Genomics·2017· 46 citedOpen Access
A targeted next generation sequencing assay to characterize relevant cancer variants in solid tumor samples.
Journal of Clinical Oncology·2016
Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development
PLoS ONE·2015· 12 citedOpen Access
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
Science·2015· 597 citedOpen Access
CAGE-defined promoter regions of the genes implicated in Rett Syndrome
BMC Genomics·2014· 10 citedOpen Access
CbGRiTS: Cerebellar gene regulation in time and space
Developmental Biology·2014· 24 cited
<i>Wls</i>Provides a New Compartmental View of the Rhombic Lip in Mouse Cerebellar Development
Journal of Neuroscience·2014· 55 citedOpen Access
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
Proceedings of the National Academy of Sciences·2014· 134 citedOpen Access
A promoter-level mammalian expression atlas
Nature·2014· 2.1k citedOpen Access
hkawaji/dpi1: Decomposition-based peak identification, which find peaks across a large number of TSS (transcription starting site) profiles
King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)·2013
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Frequent Co-authors

Dan Goldowitz(18), Peter Arner(13), Timo Lassmann(9), Peter Zhang(9), Douglas J. Swanson(9), Alistair R. R. Forrest(8), Hideya Kawaji(8), Masayoshi Itoh(7), Michael Detmar(6), Michela Fagiolini(6), Piero Carninci(6), J. Kenneth Baillie(5), Michiel de Hoon(5), Nicolas Bertin(5), Yuri Ishizu(5), Magda Babina(5), Anthony G Beckhouse(5), Frank Brombacher(5), Mitsuhiro Endoh(5), Lynsey Fairbairn(5)