Silvia Santamarina-Fojo

Medicine · Health Sciences

53h-index8.0kcitations105works0.02yr avg
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Research Topics

Cholesterol and Lipid Metabolism(46), Diabetes, Cardiovascular Risks, and Lipoproteins(29), Lipid metabolism and disorders(27), Drug Transport and Resistance Mechanisms(24), Peroxisome Proliferator-Activated Receptors(21)

Publications105 total

Analysis of Protein Structure-Function in Vivo: ADENOVIRUS-MEDIATED TRANSFER OF LIPASE LID MUTANTS IN HEPATIC LIPASE-DEFICIENT MICE
UNC Libraries·2021· 1 citedOpen Access
Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein
Metabolism·2009· 40 cited
Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice
Journal of Lipid Research·2006· 24 citedOpen Access
Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited
Journal of Lipid Research·2006· 61 citedOpen Access
Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet
Biochemical and Biophysical Research Communications·2006· 52 citedOpen Access
Effects of FXR in foam-cell formation and atherosclerosis development
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2006· 128 citedOpen Access
ABCA1 Overexpression in the Liver of LDLr-KO Mice Leads to Accumulation of Pro-atherogenic Lipoproteins and Enhanced Atherosclerosis
Journal of Biological Chemistry·2006· 78 citedOpen Access
Th-W57:5 Decreased plasma apoB-containing lipoprotein and atherosclerosis in ABCG5/G8 X LDLR-KO mice on ezetimibe
Atherosclerosis Supplements·2006
The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver
Journal of Lipid Research·2005· 159 citedOpen Access
The Ligand-binding Function of Hepatic Lipase Modulates the Development of Atherosclerosis in Transgenic Mice
Journal of Biological Chemistry·2004· 37 citedOpen Access
Hepatic Lipase, Lipoprotein Metabolism, and Atherogenesis
Arteriosclerosis Thrombosis and Vascular Biology·2004· 212 cited
The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter
Journal of Lipid Research·2004· 100 citedOpen Access
Hepatic ABCG5 and ABCG8 Overexpression Increases Hepatobiliary Sterol Transport but Does Not Alter Aortic Atherosclerosis in Transgenic Mice
Journal of Biological Chemistry·2004· 73 citedOpen Access
The ABCA1 Transporter Modulates Late Endocytic Trafficking
Journal of Biological Chemistry·2004· 195 citedOpen Access
Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice
Journal of Clinical Investigation·2003· 44 citedOpen Access
Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice
Journal of Clinical Investigation·2003· 51 citedOpen Access
Clinical significance of High-Density lipoproteins and the development of atherosclerosis: focus on the role of the adenosine triphosphate–Binding cassette protein A1 transporter
The American Journal of Cardiology·2003· 58 cited
Study of ABCA1 Function in Transgenic Mice
Arteriosclerosis Thrombosis and Vascular Biology·2003· 114 cited
New insights into the role of the adenosine triphosphate–binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transport
The American Journal of Cardiology·2003· 81 cited
Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway
Journal of Lipid Research·2003· 193 citedOpen Access
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Frequent Co-authors

H. Bryan Brewer(25), Alan T. Remaley(18), H Bryan Brewer(18), Marcelo Amar(13), Boris Vaisman(13), Robert D. Shamburek(11), Lita A. Freeman(10), Beverly Paigen(9), Robert F. Hoyt(9), Edward B. Neufeld(8), Charles Joyce(8), Glenda D. Talley(8), John A. Stonik(6), Gilles Lambert(6), Annie M. Bérard(6), Jamila Fruchart‐Najib(6), Klaus A. Dugi(6), Changting Haudenschild(5), Santica M. Marcovina(5), Catherine L. Knapper(5)