Ami S. Lakdawala

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.4kcitations44works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Melanoma and MAPK Pathways(9), Cancer Mechanisms and Therapy(9), Protein Structure and Dynamics(7), Cancer Treatment and Pharmacology(7), Alzheimer's disease research and treatments(5)

Publications44 total

Supplementary Figure 3 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Data from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Data from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Supplementary Figure 2 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Supplementary Figure 2 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Supplementary Figure 1 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Supplementary Figure 1 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Supplementary Figure 3 from Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885
2023Open Access
Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction
ACS Medicinal Chemistry Letters·2021· 7 citedOpen Access
Correction to Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel
ACS Medicinal Chemistry Letters·2020· 4 citedOpen Access
Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
ACS Medicinal Chemistry Letters·2019· 26 citedOpen Access
Structure–Activity and Structure–Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein–Protein Interaction
Journal of Medicinal Chemistry·2019· 91 citedOpen Access
3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent
ACS Medicinal Chemistry Letters·2018· 9 citedOpen Access
Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel
ACS Medicinal Chemistry Letters·2018· 35 citedOpen Access
Approaches to target tractability assessment – a practical perspective
MedChemComm·2018· 76 citedOpen Access
Adapting drug discovery to Artificial Intelligence
2018· 15 cited
The Identification and Pharmacological Characterization of 6-( <i>tert</i> -Butylsulfonyl)- <i>N</i> -(5-fluoro-1 <i>H</i> -indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase
Journal of Medicinal Chemistry·2016· 122 citedOpen Access
DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors
Journal of Medicinal Chemistry·2016· 268 citedOpen Access
CCDC 1474873: Experimental Crystal Structure Determination
The Cambridge Structural Database·2016Open Access
An Efficient and Highly Diastereoselective Synthesis of GSK1265744, a Potent HIV Integrase Inhibitor
Organic Letters·2015· 42 cited
page 1 of 3Next →

Frequent Co-authors

James P. Snyder(16), Lusong Luo(10), Alastair J. King(9), Denis R. Patrick(9), Roberta S. Batorsky(9), Maureen L. Ho(9), Shu Yun Zhang(9), David W. Rusnak(9), Andrew K. Takle(9), Erin Hugger(9), Lifu Wang(9), Florian A. Karreth(9), Julie C. Lougheed(9), Jae Lee(9), Thomas J. Stout(9), Earl W. May(9), Cynthia M. Rominger(9), Michael D. Schaber(9), Jerry L. Adams(9), Rooja G. Contractor(9)