Michaela Bairlein

Bayer (Germany) — Germany

Chemistry · Physical Sciences

8h-index1.1kcitations14works1.02yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(3), Pharmacogenetics and Drug Metabolism(2), Monoclonal and Polyclonal Antibodies Research(2), Hormonal Regulation and Hypertension(2), Computational Drug Discovery Methods(1)

Publications14 total

Predicting in vitro assays related to liver function using probabilistic machine learning
Toxicology·2025· 1 cited
Abstract C126: Translational pharmacokinetic/pharmacodynamic (PK/PD) modeling of novel covalent Kelch-like ECH-associated protein 1 (KEAP1) activators
Molecular Cancer Therapeutics·2023
In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites
Current Drug Metabolism·2023· 1 citedOpen Access
CCDC 1906048: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Journal of Medicinal Chemistry·2020· 31 citedOpen Access
Results from Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Effect of Finerenone on the Pharmacokinetics of Comedications
European Journal of Drug Metabolism and Pharmacokinetics·2020· 19 cited
Discovery and Characterization of the Potent and Selective P2X4 Inhibitor <i>N</i> -[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile
Journal of Medicinal Chemistry·2019· 55 citedOpen Access
Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies
European Journal of Drug Metabolism and Pharmacokinetics·2019· 95 citedOpen Access
Highly Variable Expression of CYP1A1 in Human Liver and Impact on Pharmacokinetics of Riociguat and Granisetron in Humans
Chemical Research in Toxicology·2019· 61 cited
Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
Drug Metabolism and Disposition·2015· 90 cited
Characterization of the small molecule kinase inhibitor SU11248 (Sunitinib/ SUTENT) in vitro and in vivo
2010
Proteomics strategy for quantitative protein interaction profiling in cell extracts
Nature Methods·2009· 147 cited
Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle
Molecular Cell·2008· 604 citedOpen Access
Analysis of protein kinases by quantitative chemical proteomics
GBM Fall meeting Hamburg 2007·2007

Frequent Co-authors

Henrik Daub(3), Jesper V. Olsen(3), Zoltán Greff(3), Gÿorgý Kéri(3), Clemens-Jeremias von Bühler(3), Florian Gnad(2), Felix Oppermann(2), Roman Körner(2), Olaf Stemmann(2), Matthias Mann(2), Robert E. Fricke(2), Dieter Lang(2), Simone I. Schulz(2), Hartmut Beck(2), Tobias Thaler(2), Daniel Meibom(2), Mark Meininghaus(2), Hannah Jörißen(2), Lisa Dietz(2), Carsten Terjung(2)