Ambroise Desfosses

Centre National de la Recherche Scientifique — France

Environmental Science · Physical Sciences

25h-index2.0kcitations67works5.92yr avg
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Research Topics

Bacteriophages and microbial interactions(13), Virology and Viral Diseases(9), RNA and protein synthesis mechanisms(8), Enzyme Structure and Function(8), Advanced Electron Microscopy Techniques and Applications(6)

Publications67 total

Structures of the LPOR–Chlide Complexes Imply the Basis of Membrane Remodeling and a Photocatalytic Mechanism
2025Open Access
Mechanistic insights into TTLL11 polyglutamylase–mediated primary tubulin chain elongation
Science Advances·2025· 1 citedOpen Access
A histidine switch regulates pH-dependent filament formation by the caspase-9 CARD
2025Open Access
α-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via “Catalytically Correct” Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery?
ACS Catalysis·2025Open Access
Expanding the Tubulin Code: TTLL11 Polyglutamylase Drives Elongation of Primary Tubulin Chains
2025Open Access
BPS2025 - Molecular mechanism of caspase-9 CARD oligomerization using cryo-EM and NMR spectroscopy
Biophysical Journal·2025
BPS2025 - Molecular mechanism of caspase-9 CARD oligomerization using cryo-EM and NMR spectroscopy
Biophysical Journal·2025
Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture
Nature Communications·2024· 29 citedOpen Access
Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain
Nature·2024· 23 citedOpen Access
The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination
Nature Communications·2023· 23 citedOpen Access
Structural landscape of the respiratory syncytial virus nucleocapsids
Nature Communications·2023· 26 citedOpen Access
CryoEM architecture of a native stretch-sensitive membrane microdomain
2023· 2 citedOpen Access
Targeting structural flexibility in low density lipoprotein by integrating cryo-electron microscopy and high-speed atomic force microscopy
International Journal of Biological Macromolecules·2023· 10 citedOpen Access
The structural mechanism of MCIA complex assembly links mitochondrial redox pathways
2023
Structural landscape of the Respiratory Syncytial Virus nucleocapsids
2023· 2 citedOpen Access
EGOC inhibits TOROID polymerization by structurally activating TORC1
Nature Structural & Molecular Biology·2023· 13 citedOpen Access
Structural basis of CHMP2A–CHMP3 ESCRT-III polymer assembly and membrane cleavage
Nature Structural & Molecular Biology·2023· 61 citedOpen Access
Structural basis of tankyrase activation by polymerization
Nature·2022· 39 citedOpen Access
Cryo-EM reconstruction of TNKS2 SAM-PARP filament
EMPIAR dataset·2022Open Access
Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage
2022Open Access
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Frequent Co-authors

Irina Gutsche(29), Guy Schoehn(11), Maria Bacia‐Verloop(8), Carsten Sachse(7), Alok K. Mitra(7), Rob W. H. Ruigrok(5), Robbie Loewith(5), Hélène Malet(5), Grégory Effantin(4), Karine Huard(4), Savvas N. Savvides(4), Jan Félix(4), Matthew Jessop(4), Juan Reguera(4), Martin Blackledge(3), Manoël Prouteau(3), Clélia Bourgoint(3), Michael Hons(3), Megghane Baulard(3), Hariprasad Venugopal(3)