Rebecca Croasdale

Roche Pharma AG (Germany) — Germany

Medicine · Health Sciences

11h-index1.1kcitations15works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(12), Glycosylation and Glycoproteins Research(10), HER2/EGFR in Cancer Research(3), Protein Structure and Dynamics(2), Galectins and Cancer Biology(2)

Publications15 total

TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations
Protein Engineering Design and Selection·2016· 27 citedOpen Access
XGFR*, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer
mAbs·2016· 31 citedOpen Access
A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties
Journal of Biological Chemistry·2014· 57 citedOpen Access
Characterization of the conformational dynamics of the Nek2 leucine zipper domain
Figshare·2013Open Access
Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies
mAbs·2012· 196 citedOpen Access
Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing
Protein Engineering Design and Selection·2012· 35 citedOpen Access
Development of tetravalent IgG1 dual targeting IGF-1R–EGFR antibodies with potent tumor inhibition
Archives of Biochemistry and Biophysics·2012· 45 cited
Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies
Molecular Therapy — Nucleic Acids·2012· 44 citedOpen Access
A structural and functional dissection of the cardiac stress response factor MS1
Proteins Structure Function and Bioinformatics·2011· 10 citedOpen Access
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
Proceedings of the National Academy of Sciences·2011· 458 citedOpen Access
An Undecided Coiled Coil
Journal of Biological Chemistry·2011· 38 citedOpen Access
Bispecific digoxigenin-binding antibodies for targeted payload delivery
Proceedings of the National Academy of Sciences·2011· 70 citedOpen Access
Abstract LB-212: XGFR, an Fc-engineered dual signaling inhibitor targeting IGF-1R and EGFR
Cancer Research·2011· 1 cited
Abstract 3285: Ang-2-VEGF CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 function mediates potent anti-tumoral and anti-angiogenic efficacy
Cancer Research·2011· 1 cited
Development of Tetravalent, Bispecific CCR5 Antibodies with Antiviral Activity against CCR5 Monoclonal Antibody-Resistant HIV-1 Strains
Antimicrobial Agents and Chemotherapy·2011· 62 citedOpen Access

Frequent Co-authors

Christian Klein(8), Werner Scheuer(7), Ulrich Brinkmann(7), Jürgen Schanzer(5), Jan Olaf Stracke(5), Eike Hoffmann(5), Pablo Umaña(5), Christian Gassner(4), Hubert Kettenberger(4), Claudio Sustmann(4), Wilma Lau(4), Juergen Schanzer(4), Katharina Wartha(4), Carola H. Ries(4), Jörg T. Regula(3), Guy Georges(3), Markus Thomas(3), Alexander K. Haas(3), Wolfgang Schaefer(2), Monika Bähner(2)