Beverly L. Davidson

Children's Hospital of Philadelphia — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

99h-index36.0kcitations438works5.32yr avg
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Research Topics

Virus-based gene therapy research(143), RNA Interference and Gene Delivery(107), Genetic Neurodegenerative Diseases(71), CRISPR and Genetic Engineering(55), Lysosomal Storage Disorders Research(46)

Publications437 total

Efficacy of AAV-mediated gene therapy in a sheep model of CLN1 disease
Molecular Genetics and Metabolism·2026
Temporal single-cell atlas of full-length Huntington’s disease mouse model defines stage-specific signatures of corticostriatal dysfunction
2026Open Access
Computational modeling and preclinical validation support targeting somatic instability for Huntington’s disease treatment
2026Open Access
CRISPR-mediated transcriptional activation as a mutation-independent therapeutic strategy for <i>SYNGAP1</i> -related intellectual disability
2025· 1 citedOpen Access
Author Correction: AAV-based delivery of RNAi targeting ataxin-2 improves survival and pathology in TDP-43 mice
Nature Communications·2025Open Access
Vaping in Pregnancy: Unraveling Molecular Drivers of Preeclampsia and Fetal Growth Restriction
International Journal of Molecular Sciences·2025· 1 citedOpen Access
219 Peptide insertions enhance AAV capsid tropism for airway epithelia
Journal of Cystic Fibrosis·2025
The future of gene therapy: Safer vectors, sharper focus
Molecular Therapy·2025· 5 citedOpen Access
Co‐Opting <scp>MBNL</scp> ‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy
Annals of Neurology·2025Open Access
Reversing Preeclampsia Pathology: AXL Inhibition Restores Mitochondrial Function and ECM Balance
Cells·2025· 1 citedOpen Access
AAV-based delivery of RNAi targeting ataxin-2 improves survival and pathology in TDP-43 mice
Nature Communications·2025· 7 citedOpen Access
Optimized AAV capsids for basal ganglia diseases show robust potency and distribution
Nature Communications·2025· 6 citedOpen Access
An AAV variant selected through NHP screens robustly transduces the brain and drives secreted protein expression in NHPs and mice
Science Translational Medicine·2025· 5 cited
Scouring the human Hsp70 network uncovers diverse chaperone safeguards buffering TDP-43 toxicity
2025· 1 citedOpen Access
Lipid Nanoparticles for <i>In Vivo</i> Lung Delivery of CRISPR-Cas9 Ribonucleoproteins Allow Gene Editing of Clinical Targets
ACS Nano·2025· 12 cited
Current trends in gene therapy to treat inherited disorders of the brain
Molecular Therapy·2025· 4 cited
Gene therapies for neurogenetic disorders
Trends in Molecular Medicine·2025· 11 cited
Transcriptomic Insights into Gas6-Induced Placental Dysfunction: Gene Targets for Preeclampsia Therapy
Cells·2025· 1 citedOpen Access
<i>CASP8</i> intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk
Proceedings of the National Academy of Sciences·2025· 6 citedOpen Access
Co-opting MBNL-dependent alternative splicing cassette exons to control gene therapy in myotonic dystrophy
2025Open Access
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Frequent Co-authors

Inês Martins(6), Ryan L. Boudreau(6), Henry L. Paulson(5), Scott Q. Harper(5), Robert M. Kotin(5), Jodi L. McBride(4), Haibin Xia(4), Yi Xing(4), Blake J. Roessler(4), Qinwen Mao(3), Alex Mas Monteys(3), Colleen S. Stein(3), Joseph Zabner(3), John A. Chiorini(3), Kevin P. Campbell(3), Patrick D. Staber(2), Steven Eliason(2), Linda Yang(2), DL Choi-Lundberg(2), Qing Lin(2)