April L. Lukowski

Scripps Institution of Oceanography — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

13h-index819citations34works4.32yr avg
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Research Topics

Alkaloids: synthesis and pharmacology(10), Chemical synthesis and alkaloids(8), Microbial Metabolic Engineering and Bioproduction(7), Metal-Catalyzed Oxygenation Mechanisms(7), Marine Toxins and Detection Methods(6)

Publications34 total

A searchable metadata network graph for microbiome metabolomics
2026· 1 citedOpen Access
Computational pipeline reveals nature’s untapped reservoir of halogenating enzymes
2026Open Access
Metagenomic Identification of Brominated Indole Biosynthetic Machinery from Cyanobacteria
Journal of Natural Products·2025Open Access
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects
Cell Host & Microbe·2025· 8 cited
31: METATRANSCRIPTOMICS REVEALS BACTERIAL TRANSGENES CONFERRING THE BENEFICIAL METABOLIC EFFECTS OF TIMERESTRICTED FEEDING
Gastroenterology·2025
Promiscuity in Nature Extends to Central Protein Biosynthetic Machinery
ACS Central Science·2025Open Access
Unlocking the catalytic precision of ligand-controlled enzymatic halogenation
Proceedings of the National Academy of Sciences·2024· 7 citedOpen Access
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile
Nature Chemistry·2024· 18 citedOpen Access
Enzymatic Halogenation of Terminal Alkynes
Journal of the American Chemical Society·2023· 32 citedOpen Access
Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme
2023· 3 citedOpen Access
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation
Nature·2022· 172 citedOpen Access
From Tryptophan to Toxin: Nature’s Convergent Biosynthetic Strategy to Aetokthonotoxin
Journal of the American Chemical Society·2022· 74 citedOpen Access
Harnessing <i>ortho</i>-Quinone Methides in Natural Product Biosynthesis and Biocatalysis
Journal of Natural Products·2022· 41 citedOpen Access
Design principles for site-selective hydroxylation by a Rieske oxygenase
Nature Communications·2022· 36 citedOpen Access
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation
2021· 5 citedOpen Access
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation
2021· 5 citedOpen Access
Biaryl bond formation through biocatalytic oxidative cross-coupling reactions
2021Open Access
Biaryl bond formation through biocatalytic oxidative cross-coupling reactions
2021Open Access
Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases
Nature Communications·2020· 51 citedOpen Access
The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6
Neuroscience Letters·2020· 28 citedOpen Access
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Frequent Co-authors

Alison R. H. Narayan(21), Meagan E. Hinze(8), Summer A. Baker Dockrey(8), Bradley S. Moore(6), Attabey Rodríguez Benítez(6), Troy Wymore(6), Dheeraj Khare(6), Lara E. Zetzsche(5), Jessica Yazarians(5), Suman Chakrabarty(5), Leo A. Joyce(5), Charles L. Brooks(5), Sanjoy Adak(4), Sara E. Tweedy(4), Bruce A. Palfey(4), Lauren A. M. Murray(3), Rebecca J. B. Schäfer(3), Janet L. Smith(3), M. Becker(2), Duncan C. Ellinwood(2)