Kian L. Tan

Novartis (China) — China

Chemistry · Physical Sciences

30h-index3.2kcitations132works4.82yr avg
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Research Topics

Asymmetric Hydrogenation and Catalysis(28), Catalytic C–H Functionalization Methods(24), Asymmetric Synthesis and Catalysis(21), Cyclopropane Reaction Mechanisms(15), Organometallic Complex Synthesis and Catalysis(13)

Publications132 total

Applying Active Learning toward Building a Generalizable Model for Ni-Photoredox Cross-Electrophile Coupling of Aryl and Alkyl Bromides
Journal of the American Chemical Society·2025· 7 cited
Discovery of GJG057, a Potent and Highly Selective Inhibitor of Leukotriene C4 Synthase
Journal of Medicinal Chemistry·2025· 2 cited
KakiRow: An Interactive User Experience Gamified Virtual Reality to Improve Rowing Sports Training
World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany·2025
Correction to “MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery”
Journal of Medicinal Chemistry·2024· 1 citedOpen Access
MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery
Journal of Medicinal Chemistry·2024· 14 cited
Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists
ACS Medicinal Chemistry Letters·2023· 2 citedOpen Access
Computer‐aided evaluation and exploration of chemical spaces constrained by reaction pathways
AIChE Journal·2023· 12 citedOpen Access
CCDC 2182302: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Hexafluoroisopropanol for the Selective Deactivation of Poisonous Nucleophiles Enabling Catalytic Asymmetric Cyclopropanation of Complex Molecules
ACS Catalysis·2022· 27 cited
<i>Meta</i>-Selective C–H Functionalization of Arylsilanes Using a Silicon Tethered Directing Group
Organic Letters·2022· 11 cited
A Simple Benchtop Filtration Method to Isolate Small Extracellular Vesicles from Human Mesenchymal Stem Cells
Journal of Visualized Experiments·2022· 8 cited
Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Insulin Resistance in Type 2 Diabetes Mellitus Rats
Pharmaceutics·2022· 43 citedOpen Access
Use of Green Solvents in Metallaphotoredox Cross-Electrophile Coupling Reactions Utilizing a Lipophilic Modified Dual Ir/Ni Catalyst System
The Journal of Organic Chemistry·2021· 15 cited
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry·2021· 22 cited
Crystal structure of putative fructose-1,6-bisphosphate aldolase from Candida auris
2021
Benchtop Isolation and Characterisation of Small Extracellular Vesicles from Human Mesenchymal Stem Cells
Molecular Biotechnology·2021· 44 cited
The 1.28A crystal structure of 3CL MainPro of SARS-CoV-2 with oxidized Cys145.
2020
Inverting Conventional Chemoselectivity in Pd-Catalyzed Amine Arylations with Multiply Halogenated Pyridines
Journal of the American Chemical Society·2017· 57 cited
Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling
ACS Catalysis·2017· 85 cited
Crystal structure of the periplasmic portion of outer membrane protein A (OmpA) from Capnocytophaga gingivalis
2016
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Frequent Co-authors

Robert G. Bergman(7), Jonathan A. Ellman(7), Xixi Sun(7), Amanda D. Worthy(7), Thomas E. Lightburn(6), Candice L. Joe(6), Dunwei Wang(6), Sunggi Lee(4), Chee Wun How(4), Jhi Biau Foo(4), Rui Liu(4), Guangbi Yuan(3), Carolynn Stephani(3), Yin Sim Tor(3), Qi Hao Looi(3), Hyelee Lee(2), Eric N. Jacobsen(2), Michael Dombrowski(2), Jonathan E. Grob(2), Philip G. Board(2)