Katja Mohrs

Regeneron (United States) — United States

Immunology and Microbiology · Life Sciences

24h-index3.3kcitations43works3.52yr avg
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Research Topics

Immune Cell Function and Interaction(19), CAR-T cell therapy research(10), T-cell and B-cell Immunology(9), Immunotherapy and Immune Responses(8), Parasites and Host Interactions(8)

Publications43 total

Optimally engineered HLA/peptide-specific CAR-T cells outperform TCR-T cells to eradicate solid tumors
Science Advances·2026Open Access
CAR T cells based on fully human T cell receptor–mimetic antibodies exhibit potent antitumor activity in vivo
Science Translational Medicine·2025· 2 citedOpen Access
Figure S7-10 and Table S1-2 from LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment
2024Open Access
Data from LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment
2024Open Access
Figure S2-6 from LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment
2024Open Access
Figure S1 from LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment
2024Open Access
A CD38xCD28 Costimulatory Bispecific Antibody Demonstrates Potent Preclinical Combinatorial Activity with a BCMAxCD3 T Cell-Engager
Blood·2024· 3 cited
A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
Cell Reports Medicine·2024· 17 citedOpen Access
LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment
Cancer Research·2024· 13 cited
Establishing an immunocompetent mouse model of CAR T anti-tumor efficacy for studies of therapeutic resistance
The Journal of Immunology·2024
Abstract 4134: Boosting anti-tumor immunity by promoting high endothelial venule and tertiary lymphoid structure formation in solid tumors via LTBR agonism
Cancer Research·2023
Abstract 1780: TCR-T and CAR-T cells targeting HLA-A2/MAGEA4 demonstrate differential tumor control, reflecting co-stimulatory signaling requirements
Cancer Research·2023
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning
Scientific Reports·2021· 93 citedOpen Access
A BCMAxCD3 bispecific T cell–engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells
Blood Advances·2021· 52 citedOpen Access
Abstract 4555: Selection of CD3 affinity allows generation of T-cell redirecting bispecific antibodies with unique pharmacokinetic and biodistribution properties
Cancer Research·2020· 1 cited
REGN5458, a Bispecific BCMAxCD3 T Cell Engaging Antibody, Demonstrates Robust In Vitro and In Vivo Anti-Tumor Efficacy in Multiple Myeloma Models, Comparable to That of BCMA CAR T Cells
Blood·2018· 16 cited
Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection
Mucosal Immunology·2018· 37 citedOpen Access
Intestinal helminth infection impacts the systemic distribution and function of the naive lymphocyte pool
Mucosal Immunology·2017· 25 citedOpen Access
The Mechanism of Splenic Invariant NKT Cell Activation Dictates Localization In Vivo
The Journal of Immunology·2013· 50 citedOpen Access
during Infection Production by CD8 T Cells γ for In Vivo IFN- Cutting Edge: T-bet and IL-27R Are Critical
2013
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Frequent Co-authors

Markus Mohrs(24), David J. DiLillo(15), Jessica R. Kirshner(9), John Lin(9), Georgia Perona‐Wright(8), Gavin Thurston(7), Christina Adler(6), Disi An(6), Christopher Daly(6), John C. Lin(6), Frank Kuhnert(6), Lawrence L. Johnson(5), David L. Woodland(5), Kara Olson(5), Kevin Bray(5), William C. Olson(5), T. Craig Meagher(5), Guoying Chen(5), Wei‐Yi Cheng(5), Namita T. Gupta(5)