J.K. Akintunde

Federal University of Agriculture — Nigeria

Environmental Science · Physical Sciences

14h-index726citations77works1.12yr avg
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Research Topics

Heavy Metal Exposure and Toxicity(9), Effects and risks of endocrine disrupting chemicals(6), Pesticide Exposure and Toxicity(6), Drug-Induced Hepatotoxicity and Protection(6), Cholinesterase and Neurodegenerative Diseases(6)

Publications77 total

Butylated hydroxytoluene protects against sodium arsenite-induced hepatorenal toxicities: <i>in vivo</i> and <i>in silico</i> studies
Drug and Chemical Toxicology·2025Open Access
Therapeutic impact of Garcinia kola-derived compounds against progesterone receptor in breast cancer using molecular docking
2025Open Access
Biomediators linked to penile dysfunction was inhibited by roasted cashew nut supplement through NOS/cAMP/PKA dependent inflammatory cascade in hypertensive rats exposed to mixture of fractionated hydrocarbons
Journal of Agriculture and Food Research·2025Open Access
Chemotherapeutic efficacy of curcumin against plasma and cardio-hepatorenal electrolyte disruption in dichlorvos-challenged rats via augmentation of Na⁺/K⁺-ATPase and Ca²⁺/Mg²⁺-ATPase activities
Journal of Trace Elements and Minerals·2025Open Access
Therapeutic potentials of trihydroxylflavonone-7-rhamnoglucoside against hepatocellular Lesch-Nyhan Syndrome induced by mixture of caffeine and KBrO3 via NOS/cAMP/PKA and DARPP-32, BDNF/TrkB signaling cascades
Pharmacological Research - Reports·2025
Development of therapeutic supplement using roasted-cashew-nut to protect cerebral vasoconstriction injury triggered by mixture of petroleum hydrocarbons in the hypothalamus and hippocampus of rat model
Toxicology Reports·2025Open Access
Curcumin mitigates dichlorvos-initiated multi-organ dysfunction in rats by attenuating systemic oxidative stress and brain inflammatory mRNA transcripts
Pharmacological Research - Reports·2025
Mantis religiosa egg-cake salvages ocular-vasoconstriction injury by inhibiting aldose-reductase-mediated catarractogenesis and TNF-α/NF-kB dependent inflammation caused by mixture of flavoring enhancers in an in-vivo model
SSRN Electronic Journal·2025Open Access
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats
Food and Chemical Toxicology·2024· 1 cited
Hesperidoside abolishes dichlorvos-mediated neurotoxicity in rats by suppressing oxidative stress, acetylcholinesterase inhibition, and NF-κB-p65/p53/caspase-3-mediated apoptosis
Phytomedicine Plus·2024· 2 citedOpen Access
Thymoquinone inhibits Neuroinflammatory mediators and vasoconstriction injury via NF-κB dependent NeuN/GFAP/Ki-67 in hypertensive Dams and F1 male pups on exposure to a mixture of Bisphenol-A analogues
Toxicology and Applied Pharmacology·2024· 5 cited
Vanillic acid ameliorates diethyl phthalate and bisphenol S‐induced oxidative stress and neuroinflammation in the hippocampus of experimental rats
Journal of Biochemical and Molecular Toxicology·2024· 5 cited
Intervention of roasted cashew nut supplement against endothelial renal vasoconstriction disease in hypertensive rats exposed to mixed-fractionated petroleum products
Clinical Nutrition Open Science·2024· 1 citedOpen Access
Hesperetin-7-rutinoside mitigates erythrocyte dyslipidemia and oxidative stress induced by dichlorvos
Journal of Hazardous Materials Advances·2024Open Access
Selenium nanoparticles from Corchorus olitorius corrects polycystic ovarian syndrome by inhibition of hormonal imbalance, aromatase and cellular inflammation via hypothalamic-ovarian axis in female rat
Endocrine and Metabolic Science·2024· 2 citedOpen Access
Hesperetin-7-O-rhamnoglucoside ameliorates dichlorvos-facilitated cardiotoxicity in rats by counteracting ionoregulatory, ion pumps, redox, and lipid homeostasis disruptions
Toxicology Reports·2024· 3 citedOpen Access
Selenium Nanoparticles from Corchorus Olitorius Corrects Polycystic Ovarian Syndrome by Inhibition of Hormonal Imbalance, Aromatase and Cellular Inflammation Via Hypothalamic-Ovarian Axis in Female Rat Model
SSRN Electronic Journal·2024Open Access
Targeting the AKT Pathway as a Therapeutic Strategy for Hepatocellular Carcinoma
International journal of research and scientific innovation·2024
Roasted cashew nut supplement inhibits MCP-1 and inflammatory mediators to correct hypertension related liver failure induced by mixed-fractionated petroleum products via NOS-cAMP-PKA signaling pathway in male rats
Medicine in Omics·2023· 2 citedOpen Access
Naringin corrects renal failure related to Lesch‐Nyhan disease in a rat model via NOS–cAMP–PKA and BDNF/TrkB pathways
Journal of Biochemical and Molecular Toxicology·2023· 3 cited
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Frequent Co-authors

Ganiyu Oboh(6), Adio J. Akamo(6), Aline Augusti Boligon(4), Ayodeji Mathias Adegoke(4), T.E. Akintola(4), A. E. Irondi(4), Emmanuel Oladipo Ajani(4), Ofem Effiom Eteng(4), Afolabi Akintunde Akindahunsi(3), T.V. Olayemi(3), A. D. Folayan(3), Emmanuel Anyachukwu Irondi(2), Odunayo Anthonia Taiwo(2), Adeola Oladayo Osifeso(2), Oluwafemi Adeleke Ojo(2), Daniel G. Akintunde(2), Olakunle Enock Bolarin(2), Ese O. Siemuri(2), Emmanuel Ifeanyichukwu Ugwor(2), O.S. Okoh(2)