Wei Seong Toh

National University of Singapore — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index19.6kcitations140works3.62yr avg
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Research Topics

Extracellular vesicles in disease(49), Osteoarthritis Treatment and Mechanisms(48), Mesenchymal stem cell research(42), 3D Printing in Biomedical Research(23), Pluripotent Stem Cells Research(22)

Publications137 total

Novel therapeutic topical gel approach for chronic inflammation and pain management in osteo- and viral-arthritis
Biomedicine & Pharmacotherapy·2026Open Access
Therapeutic Potential of Extracellular Vesicles: From Biogenesis, Isolation and Molecular Characterization to Addressing Translational Gaps and Regulatory Barriers
International Journal of Molecular Sciences·2026Open Access
Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
International Journal of Molecular Sciences·2026Open Access
Mitochondrial-targeted ROS scavenger delivery using selenium-doped layered double hydroxide nanocomposites for enhanced osteoarthritis therapy via inflammation suppression and macrophage metabolism reprogramming
Advanced Composites and Hybrid Materials·2026Open Access
Mesenchymal stem cell exosomes alleviate osteoarthritis by inhibiting complement activation via a CD59-dependent pathway
Arthritis Research & Therapy·2026Open Access
Orthopaedic Research in Singapore: The Past, Present, and Future
Journal of Bone and Joint Surgery·2026
Therapeutic applications of cell membrane-coated nanoparticles in oral diseases: Opportunities, challenges, and future perspectives
Dental Research·2026· 1 citedOpen Access
MiR-486-5p-modified DPSC-derived sEVs encapsulated in GelMA hydrogel promote wound healing by enhancing angiogenesis via Smurf2/TGF-β1 pathways
International Journal of Biological Macromolecules·2025
Advances in extracellular vesicle-based nanomedicine for regenerative orthopaedics
UCL Discovery (University College London)·2025
Advances in extracellular vesicle-based nanomedicine for regenerative orthopaedics
Journal of Nanobiotechnology·2025· 1 citedOpen Access
MSC-EVs alleviate osteoarthritic joint pain and degeneration by suppressing IL-1β/NGF signaling
Genes & Diseases·2025Open Access
Mitochondrial dysfunction in mesenchymal stem cells impairs osteogenesis in radiation-induced bone injury via Ca2+-NFATc1-Fis1 pathway
Cell Death and Disease·2025Open Access
Injectable Alginate/β‐TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis
Advanced Healthcare Materials·2025· 3 citedOpen Access
Mesenchymal Stem Cell Exosome and Fibrin Sealant Composite Enhances Rabbit Anterior Cruciate Ligament Repair
The American Journal of Sports Medicine·2025· 4 citedOpen Access
Melatonin-Loaded Hydrogel Modulates Circadian Rhythms and Alleviates Oxidative Stress and Inflammation to Promote Wound Healing
ACS Applied Bio Materials·2025· 3 cited
Small extracellular vesicles from 3D PCL/HA scaffold-cultured and EMF-stimulated BMSCs promote lumbar fusion via PTEN/PI3K/AKT pathway
Composites Part B Engineering·2025· 3 citedOpen Access
Multi-omics analysis of small extracellular vesicles in osteoarthritis: bridging the gap between molecular insights and clinical applications
Burns & Trauma·2025· 6 citedOpen Access
MiR-486-5p-modified sEVs encapsulated in GelMA hydrogel facilitated wound healing by targeting Smurf2/TGF-β1 pathways
2024Open Access
Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis
Bioactive Materials·2024· 30 citedOpen Access
Mesenchymal Stem Cell-Based Therapies for Temporomandibular Joint Repair: A Systematic Review of Preclinical Studies
Cells·2024· 12 citedOpen Access
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Frequent Co-authors

Tong Cao(16), Sai Kiang Lim(14), Ruenn Chai Lai(12), James Hoi Po Hui(11), Shipin Zhang(10), Hua Liu(7), Boon Chin Heng(7), Myron Spector(6), Keng Lin Wong(6), Andre Choo(5), Eng Hin Lee(5), Abdul Jalil Rufaihah(5), Kenneth W. Witwer(4), Mario Gimona(4), Dominique P.V. de Kleijn(4), Bernd Giebel(4), Kristeen Ye Wen Teo(4), Motoichi Kurisawa(4), Casper Bindzus Foldager(4), Chao Peng Ye(4)