René G. Ott

AstraZeneca (Switzerland) — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.3kcitations22works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(4), Lymphoma Diagnosis and Treatment(3), Fungal and yeast genetics research(3), Immune Cell Function and Interaction(3), Cytokine Signaling Pathways and Interactions(3)

Publications22 total

Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC: a retrospective chart review (REFLECT)
Therapeutic Advances in Medical Oncology·2021· 9 citedOpen Access
1299P Real-world treatment patterns, clinical outcomes and EGFR/T790M testing practices in patients with EGFRm advanced NSCLC and 1L EGFR TKI therapy: A retrospective multinational study (REFLECT)
Annals of Oncology·2020· 1 cited
TORC1 ensures membrane trafficking of Tat2 tryptophan permease via a novel transcriptional activator Vhr2 in budding yeast
Cellular Signalling·2020· 5 cited
Limitations of cancer care in Central and South-Eastern Europe: results of the international conference organized by the Central European Cooperative Oncology Group (CECOG)
Journal of Health Inequalities·2020· 13 citedOpen Access
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
Cancer Cell·2013· 299 citedOpen Access
c-JUN promotes BCR-ABL–induced lymphoid leukemia by inhibiting methylation of the 5′ region of Cdk6
Blood·2011· 38 citedOpen Access
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
Nature·2010· 415 cited
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
Nature·2009· 854 cited
Aglycosylated immunoglobulin G<sub>1</sub>variants productively engage activating Fc receptors
Proceedings of the National Academy of Sciences·2008· 175 citedOpen Access
Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib
Blood·2007· 90 citedOpen Access
The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling
Blood·2007· 103 citedOpen Access
JunB is a gatekeeper for B-lymphoid leukemia
Oncogene·2007· 23 cited
NPM-ALK Fusion Tyrosine Kinase of Anaplastic Large Cell Lymphoma Exerts Its Transforming Potential by Increasing Translation of JUNB through mTOR and S6K1.
Blood·2006
NPM-ALK Converts JUNB from a Tumor Suppressor to an Oncogene.
Blood·2006
STAT1 acts as a tumor promoter for leukemia development
Cancer Cell·2006· 152 citedOpen Access
Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2005· 30 cited
JunB inhibits proliferation and transformation in B-lymphoid cells
Blood·2003· 81 citedOpen Access
In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2003· 44 cited
The 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity in yeast
2003
Bremen im Dritten Reich : Anpassung, Widerstand, Verfolgung
C. Schünemann eBooks·1986· 8 cited
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Frequent Co-authors

Veronika Sexl(7), Lukas Kenner(4), Gerald Höefler(4), Michael Freissmuth(4), Jeffrey V. Ravetch(3), Karoline Kollmann(3), Gerwin Heller(3), Sabine Zöchbauer‐Müller(3), Richard Moriggl(3), Eva Weisz(3), Philipp B. Staber(3), Paul Vesely(3), Silvia Schauer(3), Werner Linkesch(3), Andelko Hrzenjak(3), Marshall E. Kadin(3), David Sternberg(3), Karin Athenstaedt(3), Günther Daum(3), Johannes F. Scheid(2)