Lori Westover

Springhouse — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index588citations17works6.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Adenosine and Purinergic Signaling(6), Wnt/β-catenin signaling in development and cancer(4), PI3K/AKT/mTOR signaling in cancer(4), Pharmacological Receptor Mechanisms and Effects(4), Protein Kinase Regulation and GTPase Signaling(3)

Publications17 total

High-Throughput Assessment of Bile Salt Export Pump Inhibition Using RapidFire-MS and DESI-MS
ACS Medicinal Chemistry Letters·2024· 6 citedOpen Access
Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
Cell chemical biology·2020· 78 citedOpen Access
Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry
Journal of Chemical Information and Modeling·2019· 33 cited
Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2013· 25 citedOpen Access
Design and Characterization of Optimized Adenosine A<sub>2A</sub>/A<sub>1</sub> Receptor Antagonists for the Treatment of Parkinson's Disease
Journal of Medicinal Chemistry·2012· 46 citedOpen Access
Aminomethyl substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists
MedChemComm·2011· 11 cited
In Vivo Characterization of a Dual Adenosine A<sub>2A</sub>/A<sub>1</sub> Receptor Antagonist in Animal Models of Parkinson’s Disease
Journal of Medicinal Chemistry·2010· 54 citedOpen Access
Methylene amine substituted arylindenopyrimidines as potent adenosine A2A/A1 antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 24 citedOpen Access
Optimization of arylindenopyrimidines as potent adenosine A2A/A1 antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 12 citedOpen Access
Discovery of a Dihydropyrimidine Series of Molecules that Selectively Mimic the Biological Actions of Calcitonin.
ChemInform·2004
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors
Bioorganic & Medicinal Chemistry·2004· 46 cited
3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3
Bioorganic & Medicinal Chemistry Letters·2004· 66 citedOpen Access
Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin
Bioorganic & Medicinal Chemistry Letters·2004· 12 cited
Synthesis and biological evaluation of novel macrocyclic bis-7-azaindolylmaleimides as potent and highly selective glycogen synthase kinase-3β (GSK-3β) inhibitors
Bioorganic & Medicinal Chemistry·2004· 34 cited
Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors
Journal of Medicinal Chemistry·2003· 82 citedOpen Access
Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3
Bioorganic & Medicinal Chemistry Letters·2003· 56 citedOpen Access
Validation of a Cell-Based Screen for Insulin Receptor Modulators by Quantification of Insulin Receptor Phosphorylation
SLAS DISCOVERY·2003· 3 citedOpen Access

Frequent Co-authors

Keith T. Demarest(10), Jun Xu(7), Barbara R. Conway(6), Brian C. Shook(6), Stefanie Rassnick(6), Kenneth J. Rhodes(6), Paul Jackson(6), Devraj Chakravarty(5), Robert H. Scannevin(5), Karen Carroll(5), Lisa Lampron(5), Gee‐Hong Kuo(4), Ronald K. Russell(4), Shawn Branum(4), Kenneth M. Wells(4), Sandra Damon(4), Scott Youells(4), Derek A. Beauchamp(4), Nathaniel Wallace(4), Jeffrey J. Crooke(4)