Ignacio Vázquez-Garćıa

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

47h-index23.4kcitations112works4.82yr avg
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Research Topics

Cancer Genomics and Diagnostics(55), Single-cell and spatial transcriptomics(22), Evolution and Genetic Dynamics(19), Genetic factors in colorectal cancer(10), CRISPR and Genetic Engineering(8)

Publications59 total

Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA
Nature·2025· 4 citedOpen Access
Uncertainty-Aware Generative Oversampling Using an Entropy-Guided Conditional Variational Autoencoder
arXiv (Cornell University)·2025Open Access
Abstract PR012: Targeting Chronic Inflammation in Ovarian Cancer Through Immune Engineering
Cancer Research·2025
Ongoing genome doubling shapes evolvability and immunity in ovarian cancer
Nature·2025· 18 citedOpen Access
The dynamic immune behavior of primary and metastatic ovarian carcinoma
npj Precision Oncology·2025· 4 citedOpen Access
CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution
PLoS Computational Biology·2025· 6 citedOpen Access
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Cancer Discovery·2025· 3 citedOpen Access
Data from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
Inferring replication timing and proliferation dynamics from single-cell DNA sequencing data
Nature Communications·2024· 7 citedOpen Access
Insights on Future Directions in Cancer Research from the AACR NextGen Stars
Cancer Discovery·2024
Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA
2024· 6 citedOpen Access
Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer
2024· 10 citedOpen Access
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Nature Biotechnology·2024· 5 citedOpen Access
Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes
Nature Genetics·2024· 21 citedOpen Access
CINner: modeling and simulation of chromosomal instability in cancer at single-cell resolution
2024· 6 citedOpen Access
Abstract 869: Single-cell DNA replication dynamics in genomically unstable cancers
Cancer Research·2024
Abstract PR012: Evolutionary dynamics of whole-genome doubling in ovarian cancer
Cancer Research·2024
Abstract 102: Transient chromosomal instability as a driver of ovarian cancer genome evolution
Cancer Research·2023
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Frequent Co-authors

Andrew McPherson(21), Sohrab P. Shah(21), Ville Mustonen(20), Gad Getz(19), David J. Adams(17), Pavana Anur(17), Paul C. Boutros(16), Samuel Aparício(16), Ignaty Leshchiner(16), Yulia Rubanova(16), Jeff Wintersinger(16), Salem Malikić(16), Martin Peifer(16), Clemency Jolly(15), Stefan C. Dentro(15), Daniel Rosebrock(15), Amit G. Deshwar(15), Kortine Kleinheinz(15), Kerstin Haase(15), Geoff Macintyre(15)