Filipa P. da Cruz

University of Cambridge — United Kingdom

Chemistry · Physical Sciences

12h-index954citations25works0.02yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(6), Malaria Research and Control(4), Crystallization and Solubility Studies(4), Bioactive Compounds and Antitumor Agents(4), X-ray Diffraction in Crystallography(4)

Publications25 total

Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination
Nature Chemistry·2022· 37 citedOpen Access
Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
Site-selective protein-modification chemistry for basic biology and drug development
Nature Chemistry·2015· 566 cited
Dual-stage triterpenoids from an African medicinal plant targeting the malaria parasite
Bioorganic & Medicinal Chemistry·2014· 22 cited
Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds
European Journal of Medicinal Chemistry·2013· 16 cited
Quinolin-4(1<i>H</i>)-imines are Potent Antiplasmodial Drugs Targeting the Liver Stage of Malaria
Journal of Medicinal Chemistry·2013· 25 cited
Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
The Journal of Infectious Diseases·2012· 110 citedOpen Access
Novel Potent Metallocenes against Liver Stage Malaria
Antimicrobial Agents and Chemotherapy·2011· 34 citedOpen Access
Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections
Bioorganic & Medicinal Chemistry·2011· 30 cited
4-C-Me-DAB and 4-C-Me-LAB—enantiomeric alkyl-branched pyrrolidine iminosugars—are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group
Tetrahedron Letters·2010· 36 cited
CCDC 744291: Experimental Crystal Structure Determination
The Cambridge Structural Database·2009Open Access
Carbon-branched carbohydrate chirons: practical access to both enantiomers of 2-C-methyl-ribono-1,4-lactone and 2-C-methyl-arabinonolactone
Tetrahedron Asymmetry·2008· 21 cited
Hydroxylated C-branched pyrrolidines, C-branched prolines and C-branched piperidines from a 2-C-methyl sugar lactone; efficient azide displacement of a tertiary triflate with inversion of configuration
Tetrahedron Letters·2008· 14 cited
3-<i>O</i>-Benzhydryl-2,5-dideoxy-2,5-imino-2-<i>C</i>-methyl-<scp>L</scp>-lyxono-1,4-lactone
Acta Crystallographica Section E Structure Reports Online·2008Open Access
1-Deoxy-<scp>D</scp>-arabinitol
Acta Crystallographica Section E Structure Reports Online·2008Open Access
Towards the biotechnological isomerization of branched sugars: d-tagatose-3-epimerase equilibrates both enantiomers of 4-C-methyl-ribulose with both enantiomers of 4-C-methyl-xylulose
Tetrahedron Letters·2008· 25 cited
CCDC 706042: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
CCDC 296601: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
2-<i>C</i>-Azidomethyl-2-deoxy-3,4-<i>O</i>-isopropylidene-<scp>D</scp>-ribono-1,5-lactone
Acta Crystallographica Section E Structure Reports Online·2005· 7 citedOpen Access
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Frequent Co-authors

George W. J. Fleet(12), Sarah F. Jenkinson(9), D.J. Watkin(7), Tiago Rodrigues(6), Miguel Prudêncio(6), K.V. Booth(5), Gonçalo J. L. Bernardes(4), Rui Moreira(4), Maria M. Mota(3), Lavinia Dunsmore(3), Claudio D. Navo(3), Julie Becher(3), Enrique Gil de Montes(3), Ana Guerreiro(3), Emily Hoyt(3), Libby Brown(3), Viviane Zelenay(3), Sigitas Mikutis(3), Jonathan Cooper(3), Isaia Barbieri(3)