Alexander A. Gimelbrant

Altius Institute for Biomedical Sciences — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index3.5kcitations65works0.42yr avg
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Research Topics

Genetic Syndromes and Imprinting(19), Epigenetics and DNA Methylation(17), Olfactory and Sensory Function Studies(10), Biochemical Analysis and Sensing Techniques(10), Genomics and Chromatin Dynamics(9)

Publications65 total

Author response: Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
2025Open Access
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
eLife·2025Open Access
Author response: Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
2025Open Access
Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
2025Open Access
Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
2025Open Access
Author Reply to Peer Reviews of Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
2025
Methylation pseudotime analysis for label-free profiling of the temporal chromatin landscape with long-read sequencing
2025Open Access
Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
2024· 3 citedOpen Access
Cell state transition analysis identifies interventions that improve control of <i>Mycobacterium tuberculosis</i> infection by susceptible macrophages
Science Advances·2023· 12 citedOpen Access
Foreign RNA spike-ins enable accurate allele-specific expression analysis at scale
Bioinformatics·2023· 5 citedOpen Access
Foreign RNA spike-ins enable accurate allele-specific expression analysis at scale
2023Open Access
Cell state transition analysis identifies interventions that improve control of <i>M. tuberculosis</i> infection by susceptible macrophages
2023Open Access
In Vivo Clonal Analysis Reveals Random Monoallelic Expression in Lymphocytes That Traces Back to Hematopoietic Stem Cells
Frontiers in Cell and Developmental Biology·2022· 2 citedOpen Access
Medium throughput protocol for genome-based quantification of intracellular mycobacterial loads and macrophage survival during in vitro infection
STAR Protocols·2022· 8 citedOpen Access
RNA sequencing-based screen for reactivation of silenced alleles of autosomal genes
G3 Genes Genomes Genetics·2021· 9 citedOpen Access
Diversity of developing peripheral glia revealed by single-cell RNA sequencing
Developmental Cell·2021· 88 citedOpen Access
Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system
2021Open Access
Replicate sequencing libraries are important for quantification of allelic imbalance
Nature Communications·2021· 24 citedOpen Access
CLONAL EPIGENETIC MOSAICISM: MECHANISM FOR CROHN’S DISEASE HETEROGENEITY
Gastroenterology·2021
CLONAL EPIGENETIC MOSAICISM: MECHANISM FOR CROHN’S DISEASE HETEROGENEITY
Inflammatory Bowel Diseases·2021
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Frequent Co-authors

Sébastien Vigneau(12), Virginia Savova(10), Andrew Chess(9), S.V. Vinogradova(8), Timothy S. McClintock(7), Saumya Gupta(7), Asia Mendelevich(5), Shivraj M. Yabaji(5), Igor Kramnik(5), Kyomi J. Igarashi(4), Anwesha Nag(4), Oleksii S. Rukhlenko(4), Boris Ν. Kholodenko(4), Clara Pereira(4), John N. Hutchinson(3), Jeannie T. Lee(3), Maisam Mitalipova(3), Kornélia Polyák(3), Shamil Sunyaev(3), Andrey A. Mironov(3)