Samantha E. Zak

United States Army Medical Research Institute of Infectious Diseases — United States

Medicine · Health Sciences

16h-index951citations26works3.02yr avg
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Research Topics

Viral Infections and Outbreaks Research(17), SARS-CoV-2 and COVID-19 Research(12), Viral Infections and Vectors(10), Hepatitis B Virus Studies(7), Viral gastroenteritis research and epidemiology(5)

Publications26 total

A Multivalent Pan-Ebolavirus Nanoparticle Vaccine Provides Protection in Rodents from Lethal Infection by Adapted Zaire and Sudan Viruses
2025· 3 citedOpen Access
Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design
Nature Communications·2024· 3 citedOpen Access
SARS-CoV-2 Aerosol and Intranasal Exposure Models in Ferrets
Viruses·2023· 3 citedOpen Access
Seroprevalence as an Indicator of Undercounting of COVID-19 Cases in a Large Well-Described Cohort
AJPM Focus·2023· 6 citedOpen Access
Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19
Antimicrobial Agents and Chemotherapy·2022· 2 citedOpen Access
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach
Bioorganic & Medicinal Chemistry·2021· 22 citedOpen Access
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy
International Journal of Biological Macromolecules·2021· 37 citedOpen Access
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays
Methods·2021· 38 citedOpen Access
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): <i>in silico</i> and <i>in vitro</i> investigations
RSC Medicinal Chemistry·2021· 24 citedOpen Access
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening and in vitro assays
2020· 3 citedOpen Access
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening and in vitro assays
2020· 2 citedOpen Access
Characterization of Ebola convalescent plasma donor immune response and psoralen treated plasma in the United States
Transfusion·2020· 36 cited
Development of an antibody cocktail for treatment of Sudan virus infection
Proceedings of the National Academy of Sciences·2020· 33 citedOpen Access
Longitudinal Human Antibody Repertoire against Complete Viral Proteome from Ebola Virus Survivor Reveals Protective Sites for Vaccine Design
Cell Host & Microbe·2020· 36 citedOpen Access
Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail
Viruses·2018· 20 citedOpen Access
Anti–Ebola Virus Antibody Levels in Convalescent Plasma and Viral Load After Plasma Infusion in Patients With Ebola Virus Disease
The Journal of Infectious Diseases·2018· 37 citedOpen Access
Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins
Journal of Biological Chemistry·2018· 13 citedOpen Access
Mechanistic and Fc requirements for inhibition of Sudan virus entry and in vivo protection by a synthetic antibody
Immunology Letters·2017· 2 citedOpen Access
Generation and characterization of protective antibodies to Marburg virus
mAbs·2017· 30 citedOpen Access
Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses
Scientific Reports·2016· 36 citedOpen Access
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Frequent Co-authors

John M. Dye(25), Russell R. Bakken(10), Andrew S. Herbert(9), Ana I. Kuehne(7), Kartik Chandran(7), Yash Gupta(6), Ravi Durvasula(6), Prakasha Kempaiah(6), Brijesh Rathi(5), Andrew S. Herbert(5), Majidat A. Muhammad(4), Ramon A. Ortiz(4), Laura I. Prugar(4), Dawid Maciorowski(4), Krysten A. Jones(4), Rahul S. Kathayat(4), Saara‐Anne Azizi(4), B.C. Dickinson(4), Jonathan R. Lai(4), James F. Barth(3)