Matthew T. Burger

Center for Global Development — United States

Medicine · Health Sciences

18h-index1.6kcitations49works5.72yr avg
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Research Topics

Cancer Mechanisms and Therapy(18), Peptidase Inhibition and Analysis(9), PI3K/AKT/mTOR signaling in cancer(7), Multiple Myeloma Research and Treatments(6), Phytochemical compounds biological activities(5)

Publications49 total

S227928: A Novel Anti-CD74 ADC with MCL-1 Inhibitor Payload for the Treatment of Acute Myeloid Leukemia (AML) and Other Hematologic Malignancies
Blood·2024· 5 citedOpen Access
Benign Adenomyoepithelioma of the Breast: A Case Report and Review of Imaging Features
Cureus·2024· 3 citedOpen Access
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody–Drug Conjugates
Bioconjugate Chemistry·2024· 9 cited
Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates
2023· 3 citedOpen Access
Supplementary Figures 1 - 5, Tables 1 - 2 from Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
2023Open Access
Data from Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
2023Open Access
Data from Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
2023Open Access
Supplementary Figures 1 - 5, Tables 1 - 2 from Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
2023Open Access
Glass transition, topology, and elastic models of Se‐based glasses
Journal of the American Ceramic Society·2023· 13 citedOpen Access
Evidence for 3-D network of P-centered pyramidal P(Se1/2)3 and quasi-tetrahedral Se P(Se1/2)3 local structures and their 3-membered ring super structure counterparts decoupled from quasi 1D- ethylene-like P2Se2+x (x = 2,1,0) chains in PxSe100−x glasses
Journal of Alloys and Compounds·2021· 6 cited
Synthesis and Structure–Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases
Journal of Medicinal Chemistry·2020· 6 citedOpen Access
Unusual Role of P–P Bonds on Melt Dynamics and Topological Phases of the Equimolar Ge<sub><i>x</i></sub>P<sub><i>x</i></sub>Se<sub>100–2<i>x</i></sub> Glass System
The Journal of Physical Chemistry C·2020· 13 cited
Design and Discovery of <i>N</i>-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic
Journal of Medicinal Chemistry·2019· 38 citedOpen Access
P04.24 MTOR signaling in glioma-associated microglia and macrophages
Neuro-Oncology·2018Open Access
Abstract DDT01-04: Pharmacological profile and anti-tumor properties of LXH254, a highly selective RAF kinase inhibitor
Cancer Research·2018· 3 cited
COMPOSÉS TRICYCLIQUES ET COMPOSITIONS UTILISÉS COMME INHIBITEURS DE KINASES
2017
Design and Discovery of <i>N</i>-(2-Methyl-5′-morpholino-6′-((tetrahydro-2<i>H</i>-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers
Journal of Medicinal Chemistry·2017· 44 citedOpen Access
CCDC 1508642: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Abstract 330: Development of a highly selective B/CRAF kinase inhibitor that exhibits antitumor activities in RAS and BRAF mutant tumors with minimal paradoxical activation
Cancer Research·2016
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold
Bioorganic & Medicinal Chemistry Letters·2016· 20 citedOpen Access
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Frequent Co-authors

Gisele Nishiguchi(14), Richard Zang(13), Wooseok Han(12), Pablo D. García(11), Jiong Lan(11), Cornelia Bellamacina(11), Tatiana Zavorotinskaya(10), Paul Feucht(10), Christine Fritsch(9), John L. Langowski(9), Yingyun Wang(9), Yumin Dai(9), Mika Lindvall(9), Jocelyn Holash(8), Sabina Pecchi(7), Charles F. Voliva(7), Gordana Atallah(7), Kay Huh(7), Alice Rico(7), Mark Knapp(6)