Richard L. Wolgemuth

Research Triangle Park Foundation — United States

Medicine · Health Sciences

9h-index416citations30works0.02yr avg
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Research Topics

Cancer Treatment and Pharmacology(7), Cancer therapeutics and mechanisms(5), Bioactive Compounds and Antitumor Agents(5), Synthesis and Reactions of Organic Compounds(4), Metal complexes synthesis and properties(3)

Publications30 total

Realizing the promise of the US food and drug administration modernization act
Clinical Therapeutics·1998· 8 cited
4-Demethoxy-3'-N-trifluoroacetyldoxorubicin. Synthesis and solid tumor activity.
PubMed·1990
ChemInform Abstract: Synthesis of 1‐Fluoro‐, 4‐Fluoro‐, and 1,4‐Difluoro‐4‐demethoxydaunomycinone. Interesting D‐Ring Analogues of Adriamycin.
ChemInform·1987
ChemInform Abstract: N‐(Cyanomethyl)‐ and N‐(2‐Methoxy‐1‐cyanoethyl)anthracyclines and Related Carboxyl Derivatives.
ChemInform·1987
ChemInform Abstract: N‐(2‐Hydroxyethyl)doxorubicin from Hydrolysis of 3′‐Deamino‐3′‐(3‐cyano‐4‐morpholinyl)doxorubicin.
ChemInform·1987
Synthesis of 1-fluoro-, 4-fluoro-, and 1,4-difluoro-4-demethoxydaunomycinone. Interesting D-ring analogs of adriamycin
The Journal of Organic Chemistry·1987· 22 cited
ChemInform Abstract: New Cyanomorpholinyl Byproduct of Doxorubicin Reductive Alkylation.
Chemischer Informationsdienst·1986
ChemInform Abstract: Total Chemical Synthesis and Antitumor Evaluation of the 9‐Aza Analogue of N‐(T rifluoroacetyl)‐4‐demethoxydaunomycin.
Chemischer Informationsdienst·1986
N-(2-Hydroxyethyl)doxorubicin from hydrolysis of 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin
Journal of Medicinal Chemistry·1986· 5 cited
N-(Cyanomethyl)- and N-(2-methoxy-1-cyanoethyl)anthracyclines and related carboxyl derivatives
Journal of Medicinal Chemistry·1986· 10 cited
New cyanomorpholinyl byproduct of doxorubicin reductive alkylation
Journal of Medicinal Chemistry·1986· 14 cited
Total chemical synthesis and antitumor evaluation of the 9-aza analog of N-(trifluoroacetyl)-4-demethoxydaunomycin
Journal of Medicinal Chemistry·1986· 13 cited
ChemInform Abstract: TOTAL CHEMICAL SYNTHESIS AND ANTITUMOR EVALUATION OF 4‐DEMETHOXY‐10,10‐DIMETHYLDAUNOMYCIN
Chemischer Informationsdienst·1985
ChemInform Abstract: INTENSELY POTENT MORPHOLINYL ANTHRACYCLINES
Chemischer Informationsdienst·1984
Total chemical synthesis and antitumor evaluation of 4-demethoxy-10,10-dimethyldaunomycin
Journal of Medicinal Chemistry·1984· 8 cited
Intensely potent morpholinyl anthracyclines
Journal of Medicinal Chemistry·1984· 137 cited
Effect of oral calcium sequestrants on urinary calcium excretion
Biochemical Medicine·1982
Gastrointestinal Sorbents for the Treatment of Uremia.
Annals of Nutrition and Metabolism·1981· 1 cited
Improved sensitivity of the BTPABA pancreatic function test in animals with meals of raw egg white
Digestive Diseases and Sciences·1979· 16 cited
Varia
Digestion·1977
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Frequent Co-authors

Joyce A. Filppi(10), A. R. Imondi(7), Dorris L. Taylor(5), K. M. Hanson(5), Bernd Simon(5), H Kather(5), Edward M. Acton(4), George L. Tong(4), Lester A. Mitscher(4), David Streeter(4), E. M. ACTON(4), G. L. TONG(4), R. P. Stradley(3), C.J. Pfeiffer(3), William Threlfall(3), F. Misaki(3), Z Sasaki(3), Koji Kimoto(3), Matthew C. Fisher(3), John Dent(3)