Safia Ouahrani‐Bettache

Centre National de la Recherche Scientifique — France

Veterinary · Health Sciences

21h-index2.1kcitations35works0.02yr avg
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Research Topics

Brucella: diagnosis, epidemiology, treatment(28), Escherichia coli research studies(10), Salmonella and Campylobacter epidemiology(9), Bacteriophages and microbial interactions(9), Burkholderia infections and melioidosis(8)

Publications35 total

Comparative Genome-Wide Transcriptome Analysis of Brucella suis and Brucella microti Under Acid Stress at pH 4.5: Cold Shock Protein CspA and Dps Are Associated With Acid Resistance of B. microti
Frontiers in Microbiology·2021· 20 citedOpen Access
Lethality of <i>Brucella microti</i> in a murine model of infection depends on the <i>wbkE</i> gene involved in O-polysaccharide synthesis
Virulence·2019· 15 citedOpen Access
Lethality of Brucella microti in a murine model of infection depends on the wbkE gene involved in O-polysaccharide synthesis (Research paper)
citaREA (Centro de Investigación y Tecnología Agroalimentaria de Aragón)·2019Open Access
La flexibilité respiratoire, facteur de pathogénicité et de persistance chez Brucella suis
HAL (Le Centre pour la Communication Scientifique Directe)·2018
RegA, of the redox-sensing system RegB/A, is a key regulator in oxygen-dependent establishment of Brucella suis persistence.
HAL (Le Centre pour la Communication Scientifique Directe)·2018
RegA Plays a Key Role in Oxygen-Dependent Establishment of Persistence and in Isocitrate Lyase Activity, a Critical Determinant of In vivo Brucella suis Pathogenicity
Frontiers in Cellular and Infection Microbiology·2017· 12 citedOpen Access
<i>Brucella suis</i> carbonic anhydrases and their inhibitors: Towards alternative antibiotics?
Journal of Enzyme Inhibition and Medicinal Chemistry·2017· 37 citedOpen Access
Global Rsh‐Dependent Transcription Profile of<i>Brucella Suis</i>During Stringent Response Unravels Adaptation to Nutrient Starvation and Cross‐Talk with Other Stress Responses
2016· 1 cited
Aromatic amino acid biosynthesis is dispensable for intramacrophagic growth of Brucella suis, despite attenuation of an aroC mutant
citaREA (Centro de Investigación y Tecnología Agroalimentaria de Aragón)·2015Open Access
Inhibition of<b>β</b>-carbonic anhydrases from<i>Brucella suis</i>with<i>C</i>-cinnamoyl glycosides incorporating the phenol moiety
Journal of Enzyme Inhibition and Medicinal Chemistry·2015· 15 citedOpen Access
Oxo- and thiooxo-imidazo[1,5-c]pyrimidine molecule library: Beyond their interest in inhibition of Brucella suis histidinol dehydrogenase, a powerful protection tool in the synthesis of histidine analogues
Bioorganic & Medicinal Chemistry Letters·2014· 7 cited
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis
Biochimie·2013· 14 cited
Global Rsh-dependent transcription profile of Brucella suisduring stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses
BMC Genomics·2013· 41 citedOpen Access
The virB Operon Is Essential for Lethality of Brucella microti in the Balb/c Murine Model of Infection
The Journal of Infectious Diseases·2011· 28 cited
Synthesis and biological evaluation of a new class of anti-brucella compounds targeting histidinol dehydrogenase: α-O-arylketones and α-S-arylketones derived from histidine
MedChemComm·2011· 6 cited
A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth
Bioorganic & Medicinal Chemistry·2010· 79 citedOpen Access
The New Species<i>Brucella microti</i>Replicates in Macrophages and Causes Death in Murine Models of Infection
The Journal of Infectious Diseases·2010· 61 citedOpen Access
Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from <i>Brucella suis</i>
Journal of Medicinal Chemistry·2010· 103 cited
Identification and Isolation of <i>Brucella suis</i> Virulence Genes Involved in Resistance to the Human Innate Immune System
Infection and Immunity·2007· 3 citedOpen Access
Characterization of SP41, a surface protein of Brucella associated with adherence and invasion of host epithelial cells
Cellular Microbiology·2006· 77 citedOpen Access
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Frequent Co-authors

Stephan Köhler(26), Jean‐Pierre Liautard(11), Alessandra Occhialini(10), Jean‐Yves Winum(7), María Pilar Jiménez de Bagüés(7), Véronique Jubier-Maurin(7), Sascha Al Dahouk(6), Jacques Teyssier(4), Jacques Dornand(4), Nabil Hanna(4), Vincent Foulongne(3), Gisèle Bourg(3), M Ramuz(3), Antoine Gross(3), A Terraza(3), Françoise Porte(3), Pascale Joseph(3), François Turtaut(3), Jean‐Louis Montero(3), Daniela Vullo(3)