Sai‐Yang Zhang

Zhengzhou University — China

Chemistry · Physical Sciences

29h-index2.4kcitations132works7.52yr avg
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Research Topics

Synthesis and biological activity(45), Synthesis and Biological Evaluation(23), Click Chemistry and Applications(21), Ubiquitin and proteasome pathways(14), Histone Deacetylase Inhibitors Research(13)

Publications131 total

Design and optimization of selective and potent LSD1 inhibitors with tranylcypromine-pyrimidine scaffold for the treatment of acute myeloid leukemia
Bioorganic Chemistry·2026
Anthocyanin-rich Chinese jujube fruit: A natural source of bioactive compounds and coloring agents for application in nutraceutical foods
Future Foods·2025Open Access
Advances in light-controllable PROTACs: Design strategies, therapeutic applications and current challenges
Bioorganic Chemistry·2025
Primordial Black Holes as Seeds for Extremely Overmassive AGN Observed by JWST
arXiv (Cornell University)·2025Open Access
Hydrazide-based HDAC inhibitors and PROTAC degraders in drug discovery: Recent developments and therapeutic applications
Chinese Chemical Letters·2025
Chalcones and their derivatives as inhibitors of key ABC transporters (ABCB1, ABCG2) to overcome tumor multidrug resistance
Bioorganic Chemistry·2025· 2 cited
Discovery of novel 1,2,3-triazole arylamide derivatives bearing dithiocarbamate moiety as dual inhibitors of tubulin and LSD1 with potent anticancer activity
European Journal of Medicinal Chemistry·2025· 5 cited
Design and synthesis of formononetin-piperazine hybrids that inhibit the migration and growth of MGC-803 cells
Medicinal Chemistry Research·2025· 1 cited
A black hole in a near-pristine galaxy 700 million years after the Big Bang
ArXiv.org·2025· 6 citedOpen Access
Nanoparticles and Their Impact on Epigenetic Mechanisms: Insights and Implications
Advanced Therapeutics·2025· 4 cited
Discovery of novel coumarin-sulfonates as tubulin polymerization inhibitors targeting the colchicine-binding site with potent anticancer activities
Bioorganic & Medicinal Chemistry Letters·2025· 2 cited
ALK-based dual inhibitors: Focus on recent development for non-small cell lung cancer therapy
European Journal of Medicinal Chemistry·2025· 5 cited
Current Progress of Hederagenin and Its Derivatives for Disease Therapy (2017–Present)
Molecules·2025· 3 citedOpen Access
Discovery of novel tranylcypromine-indazole-based derivatives as LSD1 inhibitors for acute myeloid leukemia treatment
European Journal of Medicinal Chemistry·2025· 4 cited
Thienopyrimidine: A promising scaffold in the development of kinase inhibitors with anticancer activities
Bioorganic & Medicinal Chemistry·2025· 4 cited
Discovery of 2,4-diaminopyrimidine derivatives as potent inhibitors of FAK capable of activating the Hippo pathway for the treatment of esophageal squamous cell carcinoma
European Journal of Medicinal Chemistry·2025· 5 citedOpen Access
Discovery of novel thienopyridine indole derivatives as inhibitors of tubulin polymerization targeting the colchicine-binding site with potent anticancer activities
European Journal of Medicinal Chemistry·2025· 13 cited
The pan-cancer analysis of LRG1 and its potential role in kidney renal clear cell carcinoma
RSC Medicinal Chemistry·2025Open Access
Research on motion planning of 6-DOF manipulator based on optimization algorithm
2024
A short overview of dual targeting HDAC inhibitors
Future Medicinal Chemistry·2024· 6 citedOpen Access
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Frequent Co-authors

Jian Song(33), Yanbing Zhang(22), Dong‐Jun Fu(15), Hong‐Min Liu(11), Xin-Yi Tian(10), Cheng‐Yun Jin(9), Xiaolin Zi(8), Yin-Ru Li(8), Guang-Xi Yu(7), Xiujuan Liu(6), Ruo-Han Zhao(6), Shenghui Wang(6), Shuo Yuan(5), Bowen Wu(5), Yingchao Liu(5), Ting Zhu(5), Xiang-Jing Fu(5), Lirong Zhang(4), Jiahuan Li(4), Jiajia Yang(4)