Michael Sattler

Target (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

76h-index26.0kcitations572works4.32yr avg
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Research Topics

RNA Research and Splicing(153), RNA and protein synthesis mechanisms(128), RNA modifications and cancer(113), Protein Structure and Dynamics(78), Enzyme Structure and Function(51)

Publications572 total

A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis
Cell·2025· 5 citedOpen Access
Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering
Structure·2025Open Access
Evolutionary Remodelling of a Remnant GET-Pathway Factor into PEX38, a Novel and Essential Peroxin in <i>Euglenozoa</i>
2025· 1 citedOpen Access
Conformational Quenching in an Engineered Lipocalin Protein Achieves High Affinity Binding to the Toxin Colchicine
Angewandte Chemie·2025Open Access
Conformational Quenching in an Engineered Lipocalin Protein Achieves High Affinity Binding to the Toxin Colchicine
Angewandte Chemie International Edition·2025Open Access
It’s Not Always Crystal Clear: In-Pocket Analysis for Understanding Binding Site Microenvironment Properties
2025Open Access
QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites
2025Open Access
Genotype-Phenotype Correlation in RBM10-Associated Syndromes – How Variant Function Shapes a Broad Phenotypic Landscape
2025Open Access
A universal model for drug-receptor interactions
2025Open Access
Inter-domain flexibility and AI-guided sequence optimization enhance de novo enzyme function
2025· 1 citedOpen Access
Deciphering the RNA recognition by Musashi-1 to design protein and RNA variants for <i>in vitro</i> and <i>in vivo</i> applications
Nucleic Acids Research·2025· 1 citedOpen Access
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability
Nature Communications·2025· 2 citedOpen Access
Molecular mechanisms of biomolecular condensate formation in <i>Drosophila melanogaster</i> siRNA biogenesis
Nucleic Acids Research·2025Open Access
Quantum mechanics-driven structure-activity relationship study of PEX5-PEX14 protein-protein interaction inhibitors based on a dibenzo[b,e]azepin-6(6H)-one scaffold
European Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Signal Transducer and Activator of Transcription 3 (STAT3) Variant p.K709N Causes Hyper‐IgE Syndrome Likely by Impaired STAT3‐Dimer Formation
European Journal of Immunology·2025Open Access
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
Cell·2025· 20 citedOpen Access
Unique conformational dynamics and protein recognition of A-to-I hyper-edited dsRNA
Nucleic Acids Research·2025· 3 citedOpen Access
How does a credible voice sound?
The Journal of the Acoustical Society of America·2025Open Access
Abstract 1962 Role of histone N-terminal acetylation in genome integrity
Journal of Biological Chemistry·2025Open Access
The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle
2025Open Access
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Frequent Co-authors

Bernd Simon(9), Tobias Madl(7), André Mourão(5), Günter Stier(5), Stephen W. Fesik(4), Cameron D. Mackereth(4), Arie Geerlof(4), Grzegorz M. Popowicz(3), Robert Meadows(3), John E. Harlan(3), Andreas Lingel(3), Elisa Izaurralde(3), Remco Sprangers(3), Katia Zanier(3), Juan Valcárcel(3), Andreas Schlundt(3), Dierk Niessing(3), Maceler Aldrovandi(2), Jonas Wanninger(2), Bettina Proneth(2)