Jan Brábek

Charles University — Czech Republic

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index4.2kcitations128works3.12yr avg
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Research Topics

Cellular Mechanics and Interactions(38), Cell Adhesion Molecules Research(20), Protein Kinase Regulation and GTPase Signaling(13), Mitochondrial Function and Pathology(12), Metabolism and Genetic Disorders(12)

Publications128 total

Cancer invasion plasticity during the metastatic cascade: strategies to survive and thrive
Cancer Letters·2026
Design and Synthesis of Actin-Targeting 10-Phenoxy Cytochalasan Analogues: Balancing Cytotoxicity and Migrastatic Activity
ACS Medicinal Chemistry Letters·2026Open Access
The potential of cytochalasins and other cytochalasans as drugs targeting cancer cell invasiveness and metastasis
European Journal of Medicinal Chemistry·2025
Migrastatic Therapy as a Potential Game-Changer in Adaptive Cancer Treatment
2024· 1 citedOpen Access
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
eLife·2024· 9 citedOpen Access
Author response: Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
2024Open Access
Author response: Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
2024Open Access
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
2024Open Access
Miro1 regulates the migratory properties and metastatic potential of B16 melanoma cells
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024
Microtubule‐associated <scp>NAV3</scp> regulates invasive phenotypes in glioblastoma cells
Brain Pathology·2024· 5 citedOpen Access
NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation
Frontiers in Pharmacology·2024· 7 citedOpen Access
Educate, not kill: treating cancer without triggering its defenses
Trends in Molecular Medicine·2024· 12 citedOpen Access
Author Response: Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway
2024Open Access
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway
2024· 2 citedOpen Access
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
eLife·2024· 7 citedOpen Access
Suppression of the growth and metastasis of mouse melanoma by Taenia crassiceps and Mesocestoides corti tapeworms
Frontiers in Immunology·2024· 4 citedOpen Access
Mitochondrial <scp>HER</scp>2 stimulates respiration and promotes tumorigenicity
European Journal of Clinical Investigation·2024· 6 citedOpen Access
Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety
RSC Medicinal Chemistry·2023· 9 citedOpen Access
Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
eLife·2023· 4 citedOpen Access
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
2023· 2 citedOpen Access
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Frequent Co-authors

Daniel Rösel(41), Karel Smetana(10), Lukáš Lacina(8), Ondřej Tolde(8), Aneta Gandalovičová(6), Pavel Veselý(6), Vladimı́r Čermák(5), Milan Jakubek(5), Ben Fabry(5), Radoslav Janoštiak(5), Steven K. Hanks(5), Barbora Dvořánková(5), Marián Novotný(4), Michal Kolář(4), Petr Folk(4), Karolína Strnadová(4), Lenka Koudelková(4), Claudia Tanja Mierke(3), Ladislav Merta(3), Daniela Paňková(3)