LeAnn J. Howe

University of British Columbia — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.7kcitations42works0.82yr avg
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Research Topics

Genomics and Chromatin Dynamics(31), Epigenetics and DNA Methylation(10), RNA modifications and cancer(9), RNA Research and Splicing(8), Plant Molecular Biology Research(6)

Publications42 total

Human MeCP2 binds to promoters and inhibits transcription in an unmethylated yeast genome
Genetics·2025· 2 citedOpen Access
Human MeCP2 binds to promoters and inhibits transcription in an unmethylated S. cerevisiae genome
2024· 1 citedOpen Access
PAN deadenylase ensures proper mitosis under conditions of microtubule stress by regulating spindle integrity and promoting cell survival
2024Open Access
A fluorescent assay for cryptic transcription in <i>Saccharomyces cerevisiae</i> reveals novel insights into factors that stabilize chromatin structure on newly replicated DNA
Genetics·2024Open Access
A fluorescent assay for cryptic transcription in <i>Saccharomyces cerevisiae</i> reveals novel insights into factors that stabilize chromatin structure on newly replicated chromatin
2023Open Access
Reply to: Pitfalls in using phenanthroline to study the causal relationship between promoter nucleosome acetylation and transcription
Nature Communications·2022· 1 citedOpen Access
43rd International Asilomar Chromatin, Chromosomes, and Epigenetics Conference
Biochemistry and Cell Biology·2022
Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells
Antioxidants·2021· 18 citedOpen Access
Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells
The Journal of Nutritional Biochemistry·2021· 24 citedOpen Access
Transcription shapes genome-wide histone acetylation patterns
Nature Communications·2021· 150 citedOpen Access
The Function and Evolution of Motile DNA Replication Systems in Ciliates
Current Biology·2020· 90 citedOpen Access
The majority of histone acetylation is a consequence of transcription
2019· 3 citedOpen Access
Transcription Promotes the Interaction of the FAcilitates Chromatin Transactions (FACT) Complex with Nucleosomes in <i>Saccharomyces cerevisiae</i>
Genetics·2018· 59 citedOpen Access
Transcription promotes the interaction of the FAcilitates Chromatin Transactions (FACT) complex with nucleosomes in <i>S. cerevisiae</i>
2018Open Access
Viral proteins as a potential driver of histone depletion in dinoflagellates
Nature Communications·2018· 49 citedOpen Access
Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in<i>Saccharomyces cerevisiae</i>
Genetics·2017· 10 citedOpen Access
Histone H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone Acetyltransferase in <i>Saccharomyces cerevisiae</i>
Genetics·2017· 28 citedOpen Access
Histone H3K4 and H3K36 methylation promotes recruitment, but not activity, of the NuA3 histone acetyltransferase complex in <i>S. cerevisiae</i>
2016Open Access
Divergent Residues Within Histone H3 Dictate a Unique Chromatin Structure in <i>Saccharomyces cerevisiae</i>
Genetics·2015· 16 citedOpen Access
Polarization of the Endoplasmic Reticulum by ER-Septin Tethering
Cell·2014· 107 citedOpen Access
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Frequent Co-authors

Benjamín Martín(14), Jerry L. Workman(7), Juan Ausió(7), Julie Brind’Amour(5), Barry P. Young(5), Adam Chruscicki(5), Christopher Loewen(5), Joshua A.R. Brown(5), Kristoffer N. Jensen(4), Jennifer K. Choi(4), Vicki E. Maltby(4), Kristina L. McBurney(4), Christine E. Brown(3), Patrick A. Grant(3), Matthew C. Lorincz(3), Nicholas A. T. Irwin(3), Maggie Y.M. Ling(3), Ellia Gao(3), John R. Yates(2), Sam John(2)