Ryan D. Heselpoth

Rockefeller University — United States

Environmental Science · Physical Sciences

16h-index879citations27works0.02yr avg
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Research Topics

Bacteriophages and microbial interactions(20), Genomics and Phylogenetic Studies(7), Bacterial Genetics and Biotechnology(5), Probiotics and Fermented Foods(4), RNA and protein synthesis mechanisms(3)

Publications27 total

Second-generation lysocins as therapeutics for treating <i>Pseudomonas aeruginosa</i> infections
Antimicrobial Agents and Chemotherapy·2025Open Access
Engineered Lysin-Derived Peptide as a Potent Antimicrobial for Acne Vulgaris
Antibiotics·2025Open Access
Thermal Characterization and Interaction of the Subunits from the Multimeric Bacteriophage Endolysin PlyC
Biology·2023· 1 citedOpen Access
PaP1, a Broad-Spectrum Lysin-Derived Cationic Peptide to Treat Polymicrobial Skin Infections
Frontiers in Microbiology·2022· 25 citedOpen Access
Thermal characterization and interaction of the subunits from the multimeric bacteriophage endolysin PlyC
2022Open Access
Using synthetic activity to design ultra-potent antibody cocktails
2021· 6 citedOpen Access
High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A <i>Streptococcus</i>
Molecular Microbiology·2021· 12 cited
Enzybiotics: Endolysins and Bacteriocins
2021· 16 cited
Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7
Scientific Reports·2020· 40 citedOpen Access
Searching for a Bacteriophage Lysin to Treat <i>Corynebacterium bovis</i> in Immunocompromised Mice
Comparative Medicine·2020· 3 citedOpen Access
Structure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3)
Scientific Reports·2019· 35 citedOpen Access
Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria
Antimicrobial Agents and Chemotherapy·2019· 115 citedOpen Access
Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal
Viruses·2018· 62 citedOpen Access
Enzybiotics: Endolysins and Bacteriocins
2017· 13 cited
A bacteriophage endolysin that eliminates intracellular streptococci
eLife·2016· 76 citedOpen Access
Author response: A bacteriophage endolysin that eliminates intracellular streptococci
2016Open Access
Middle region of the<i>Borrelia burgdorferi</i>surface-located protein 1 (Lmp1) interacts with host chondroitin-6-sulfate and independently facilitates infection
Cellular Microbiology·2015· 27 citedOpen Access
Increasing the stability of the bacteriophage endolysin PlyC using rationale-based FoldX computational modeling
Protein Engineering Design and Selection·2015· 45 citedOpen Access
Quantitative analysis of the thermal stability of the gamma phage endolysin PlyG: A biophysical and kinetic approach to assaying therapeutic potential
Virology·2014· 21 cited
Characterization of AlgMsp, an Alginate Lyase from Microbulbifer sp. 6532A
PLoS ONE·2014· 81 citedOpen Access
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Frequent Co-authors

Daniel Nelson(19), Vincent A. Fischetti(9), Sara B. Linden(7), Chad W. Euler(3), M S Mitchell(3), J. Todd Hoopes(3), D. Travis Gallagher(3), Yang Shen(3), Steven M. Swift(3), John Moult(3), Xiaoran Shang(3), Julia Greenfield(3), Osnat Herzberg(3), Sheena McGowan(2), Ashley M. Buckle(2), Patrick Bales(2), Marilia Barros(2), Tarek Vennemann(2), Yizhou Yin(2), Dennis D. Spencer(2)