Ruby H. P. Law

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index5.3kcitations126works0.32yr avg
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Research Topics

Protease and Inhibitor Mechanisms(27), Mitochondrial Function and Pathology(15), ATP Synthase and ATPases Research(14), Photosynthetic Processes and Mechanisms(12), Streptococcal Infections and Treatments(11)

Publications126 total

The Halo Fluorescence Fibrinolysis (HoFF) Test Identifies Hypofibrinolytic Phenotypes in Patients with Sepsis
Journal of Thrombosis and Haemostasis·2025
Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin
ChemMedChem·2024· 1 citedOpen Access
Impact of Plasminogen on <i>Clostridioides difficile</i> Colitis
Biochemistry·2024Open Access
Proteoform-Resolved Profiling of Plasminogen Activation Reveals Novel Abundant Phosphorylation Site and Primary N-Terminal Cleavage Site
Molecular & Cellular Proteomics·2023· 2 citedOpen Access
A mechanism for hereditary angioedema caused by a methionine-379–to–lysine substitution in kininogens
Blood·2023· 7 citedOpen Access
Forms of Hereditary Angioedema That Are Independent of Kallikrein and Factor XIIa System
Blood·2023Open Access
A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Fragment-based and structure-guided discovery of perforin inhibitors
European Journal of Medicinal Chemistry·2023· 5 citedOpen Access
A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
Preprints.org·2023· 1 citedOpen Access
Towards a better understanding of the role of Annexin A2–S100A10 tetramer in diseases
Acta Crystallographica Section A Foundations and Advances·2023Open Access
A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
Preprints.org·2023· 1 citedOpen Access
Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies
ACS Chemical Biology·2023· 1 cited
The role of NINJ1 protein in programmed cellular destruction
Nature·2023· 9 cited
Front Cover: Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors (ChemMedChem 6/2023)
ChemMedChem·2023Open Access
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors
ChemMedChem·2023· 2 citedOpen Access
Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity
Journal of Biological Chemistry·2022· 9 citedOpen Access
A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen
Blood·2022· 30 citedOpen Access
Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains
Blood Advances·2022· 35 citedOpen Access
Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface
Gastroenterology·2020· 11 citedOpen Access
Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)
Angewandte Chemie International Edition·2020Open Access
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Frequent Co-authors

James C. Whisstock(38), Ashley M. Buckle(15), Robert N. Pike(11), Tom T. Caradoc-Davies(10), Phillip I. Bird(9), Ilia Voskoboinik(9), Michelle A. Dunstone(8), Joseph A. Trapani(8), Paul J. Conroy(8), Carlos J. Rosado(7), Christopher G. Langendorf(7), James A. Irving(7), Stephen Bottomley(5), A. Ian Smith(5), Jamie Rossjohn(5), Adam J. Quek(5), Rodney J. Devenish(5), Phillip Nagley(5), Guojie Wu(5), Sheena McGowan(4)