Andrea Moir

AstraZeneca (United Kingdom) — United Kingdom

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

10h-index275citations12works0.02yr avg
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Research Topics

Drug Solubulity and Delivery Systems(7), Gastroesophageal reflux and treatments(3), Helicobacter pylori-related gastroenterology studies(2), Drug Transport and Resistance Mechanisms(2), Monoclonal and Polyclonal Antibodies Research(2)

Publications12 total

Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis
The AAPS Journal·2023· 12 cited
Acalabrutinib Maleate Tablets: The Physiologically Based Biopharmaceutics Model behind the Drug Product Dissolution Specification
Molecular Pharmaceutics·2023· 11 cited
Challenges and Strategies for Solubility Measurements and Dissolution Method Development for Amorphous Solid Dispersion Formulations
The AAPS Journal·2022· 33 citedOpen Access
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults
Pharmaceutical Research·2022· 14 cited
Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series
Pharmaceutics·2022· 14 citedOpen Access
Biorelevant in vitro Tools and in silico Modeling to Assess pH-Dependent Drug-drug Interactions for Salts of Weak Acids: Case Example Potassium Raltegravir
Journal of Pharmaceutical Sciences·2021· 4 cited
Evaluating the impact of acid-reducing agents on drug absorption using biorelevant in vitro tools and PBPK modeling - case example dipyridamole
European Journal of Pharmaceutical Sciences·2021· 15 cited
Prediction of plasma profiles of a weakly basic drug after administration of omeprazole using PBPK modeling
European Journal of Pharmaceutical Sciences·2020· 10 cited
IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies
European Journal of Pharmaceutics and Biopharmaceutics·2020· 37 citedOpen Access
Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part II. A mechanistic PBPK model for IR formulation comparison, proton pump inhibitor drug interactions, and administration with acidic juices
European Journal of Pharmaceutics and Biopharmaceutics·2019· 49 cited
Impact of Acid-Reducing Agents on Gastrointestinal Physiology and Design of Biorelevant Dissolution Tests to Reflect These Changes
Journal of Pharmaceutical Sciences·2019· 29 cited
A comparative study of the allomerization reaction of chlorophyll a and bacteriochlorophyll a
Journal of the Chemical Society Perkin Transactions 2·1998· 47 cited

Frequent Co-authors

Xavier Pépin(6), James Mann(6), Εva Karlsson(5), Jennifer Dressman(5), Domagoj Šegregur(4), Richard A. Barker(3), Talia Flanagan(3), David B. Turner(3), Christophe Tistaert(3), Adam S. Darwich(2), Shruthi Vaidhyanathan(2), Tycho Heimbach(2), Natalie Sanderson(1), E. J. Meehan(1), A. Philip Plumb(1), George R. Bailey(1), Dean Murphy(1), Cecile M. Krejsa(1), Marilee Andrew(1), Timothy G. Ingallinera(1)