Andrea D. Eckhart

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index4.5kcitations93works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(52), Cardiac electrophysiology and arrhythmias(20), Ion channel regulation and function(14), Cardiac Ischemia and Reperfusion(10), Protein Kinase Regulation and GTPase Signaling(9)

Publications93 total

Regulation of Vascular Smooth Muscle Growth by -Adrenoreceptor Subtypes in Vitro and in Situ
UNC Libraries·2021· 1 citedOpen Access
Characterization of the  1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle
UNC Libraries·2021· 1 citedOpen Access
Erratum to: Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism
Journal of Inherited Metabolic Disease·2016· 4 citedOpen Access
α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance
Diabetes Care·2016· 126 citedOpen Access
Persistent increases in Ca2+ influx through Cav1.2 shortens action potential and causes Ca2+ overload-induced afterdepolarizations and arrhythmias
Basic Research in Cardiology·2015· 30 citedOpen Access
Abstract #277: Outcomes of a Standardized Protocol for Diabetes Management in Surgical Inpatients
Endocrine Practice·2015
Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism
Journal of Inherited Metabolic Disease·2015· 214 citedOpen Access
A Novel Test for IGT Utilizing Metabolite Markers of Glucose Tolerance
Journal of Diabetes Science and Technology·2014· 45 citedOpen Access
Understanding the Apothecaries Within: The Necessity of a Systematic Approach for Defining the Chemical Output of the Human Microbiome
Clinical and Translational Science·2014· 12 citedOpen Access
Understanding Tumour Metabolic Reprogramming with Metabolomics
Encyclopedia of Life Sciences·2013
Exploiting functional domains of GRK2/3 to alter the competitive balance of pro‐ and anticontractile signaling in airway smooth muscle
The FASEB Journal·2013· 21 citedOpen Access
Metabolomics as a Key Integrator for “Omic” Advancement of Personalized Medicine and Future Therapies
Clinical and Translational Science·2012· 51 citedOpen Access
S100A1 Genetically Targeted Therapy Reverses Dysfunction of Human Failing Cardiomyocytes
Journal of the American College of Cardiology·2011· 74 citedOpen Access
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy
Journal of Molecular and Cellular Cardiology·2010· 109 cited
The Inotropic Peptide βARKct Improves βAR Responsiveness in Normal and Failing Cardiomyocytes Through G <sub>βγ</sub> -Mediated L-Type Calcium Current Disinhibition
Circulation Research·2010· 49 citedOpen Access
Impaired neoangiogenesis in β<sub>2</sub>–adrenoceptor gene‐deficient mice: restoration by intravascular human β<sub>2</sub>–adrenoceptor gene transfer and role of NFκB and CREB transcription factors
British Journal of Pharmacology·2010· 53 citedOpen Access
Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms
Circulation Research·2010· 130 citedOpen Access
G Protein-coupled Receptor Kinase (GRK) Inhibition Preferentially Augments Beta-2-adrenergic Receptor (b2AR) Signaling And Function In Airway Smooth Muscle (ASM)
2010
Mineralocorticoid receptors, corticosteroids and the heart: where do we stand?
Journal of Hypertension·2010· 2 cited
Regulation of GPCR signaling in Hypertension
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2010· 101 citedOpen Access
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Frequent Co-authors

Walter J. Koch(30), Patrick Most(11), David M. Harris(11), Erhe Gao(9), J. Kurt Chuprun(7), Sven T. Pleger(7), Hugo A. Katus(7), Matthieu Boucher(6), Mirko Völkers(6), Andrew Remppis(6), Stéphanie Pesant(6), Janelle R. Keys(6), Philip Raake(4), Leif Erik Vinge(4), Xiongwen Chen(4), Brent R. DeGeorge(4), Hendrik T. Tevaearai(4), James E. Faber(4), Henriette Brinks(4), Ruihai Zhou(4)