Damian M. Cummings

University College London — United Kingdom

Neuroscience · Life Sciences

27h-index2.9kcitations63works0.72yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(21), Genetic Neurodegenerative Diseases(21), Alzheimer's disease research and treatments(18), Neuroinflammation and Neurodegeneration Mechanisms(18), Neurological disorders and treatments(13)

Publications63 total

Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue
2025Open Access
Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer’s disease mouse model
Nature Communications·2025· 1 citedOpen Access
The Microglial <i>Trem2</i> R47H Alzheimer’s Disease Risk Variant Impairs Early Hippocampal Synaptic Remodeling
2025Open Access
Isotope Encoded Spatial Biology Identifies Amyloid Plaque-Age-Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity
2025Open Access
Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue
SSRN Electronic Journal·2025Open Access
Age- and amyloid-β-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimer’s disease without mutations in <i>MAPT</i>
2024· 1 citedOpen Access
Isotope Encoded chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity
2024· 4 citedOpen Access
Sodium channel inhibitors alter the progress of tangle development in a mouse model of dementia
2024Open Access
Review for "Optogenetics in chronic neurodegenerative diseases, controlling the brain with light: A systematic review"
2024
Review for "Optogenetics in chronic neurodegenerative diseases, controlling the brain with light: A systematic review"
2023
Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo
Advanced Materials Technologies·2023· 16 citedOpen Access
Review for "The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives"
2023
Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology
Cell Reports·2022· 67 citedOpen Access
Upregulation of <i>Trem2</i> expression occurs exclusively on microglial contact with plaques
2022Open Access
Upregulation of &lt;i&gt;Trem2&lt;/i&gt; Expression Occurs Exclusively on Microglial Contact with Plaques
SSRN Electronic Journal·2022Open Access
Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia.
Apollo (University of Cambridge)·2021Open Access
Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
Molecular Neurodegeneration·2021· 74 citedOpen Access
Additive manufacturing of multielectrode arrays for biotechnological applications
Materials Advances·2021· 3 citedOpen Access
<i>Trem2</i> promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions
Human Molecular Genetics·2020· 201 citedOpen Access
Multiphoton fabrication of bioelectronics
Lancaster EPrints (Lancaster University)·2020
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Frequent Co-authors

Frances A. Edwards(23), Derviş A. Salih(14), Carlos Cepeda(11), John Hardy(10), Kerry Murphy(10), Michael S. Levine(9), Austen J. Milnerwood(9), Sarat C. Vatsavayai(9), Mark C. Hirst(9), Wenfei Liu(8), Glenn Dallérac(8), Jack Wood(7), Jörg Hanrieder(7), Jill Richardson(6), Katie Stringer(6), Sevinç Bayram(5), Payam Rezaie(5), Mar Matarín(4), Véronique M. André(4), Rui Wang(4)