Orly Lazarov

Illinois College — United States

Neuroscience · Life Sciences

41h-index8.8kcitations99works3.62yr avg
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Research Topics

Neurogenesis and neuroplasticity mechanisms(47), Alzheimer's disease research and treatments(46), Neuroinflammation and Neurodegeneration Mechanisms(18), Nerve injury and regeneration(16), Neuroscience and Neuropharmacology Research(8)

Publications99 total

Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in Alzheimer’s disease mouse models
Nature Communications·2025Open Access
Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in Alzheimer’s disease mouse models
2025
Amyloid precursor protein dosage normalization rescues neurogenesis and Alzheimer’s Disease phenotypes associated with Down Syndrome
2025Open Access
Amyloid precursor protein mediates deficits in corticogenesis in Down syndrome cortical organoids
2025Open Access
Neurogenesis drives hippocampal formation-wide spatial transcription alterations in health and Alzheimer's disease
Frontiers in Dementia·2025· 1 citedOpen Access
Therapeutic modulation of neurogenesis to improve hippocampal plasticity and cognition in aging and Alzheimer's disease
Neurotherapeutics·2025· 14 citedOpen Access
Longitudinal excitation-inhibition balance altered by sex and APOE-ε4
Communications Biology·2025· 2 citedOpen Access
Mapping lipids associated with Aβ plaques in a mouse model of Alzheimer’s disease via multiscale mass spectrometry imaging
Alzheimer s & Dementia·2024Open Access
Inhibition of β-catenin signaling by Amyloid-β in endothelial cells impairs vascular barrier integrity
2024· 1 citedOpen Access
Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in an Alzheimer’s disease mouse model
2024· 2 citedOpen Access
Brain-immune interactions: implication for cognitive impairments in Alzheimer's disease and autoimmune disorders
Journal of Leukocyte Biology·2024· 4 citedOpen Access
A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.
2024· 2 citedOpen Access
Memory circuits in dementia: The engram, hippocampal neurogenesis and Alzheimer’s disease
Progress in Neurobiology·2024· 22 citedOpen Access
Temporal Alterations in White Matter in An<i>App</i>Knock-In Mouse Model of Alzheimer’s Disease
eNeuro·2024· 3 citedOpen Access
Caveolin-1 Regulates Neurogenesis and Learning and Memory by Modulation of Mitochondrial Dynamics
2023· 1 citedOpen Access
Reduced endothelial caveolin-1 underlies deficits in brain insulin signalling in type 2 diabetes
Brain·2023· 9 citedOpen Access
Adult hippocampal neurogenesis in Alzheimer’s disease: A roadmap to clinical relevance
Cell stem cell·2023· 139 citedOpen Access
Hippocampal functional connectivity across age in an App knock-in mouse model of Alzheimer's disease
Frontiers in Aging Neuroscience·2023· 14 citedOpen Access
Caveolin-1 Autonomously Regulates Hippocampal Neurogenesis Via Mitochondrial Dynamics
SSRN Electronic Journal·2023Open Access
Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons
The Journal of Experimental Medicine·2022· 56 citedOpen Access
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Frequent Co-authors

Sangram S. Sisodia(9), Michal Schwartz(8), Richard D. Minshall(5), Matthew K. Tobin(5), Michael P. Demars(5), Carolyn Hollands(5), Scott T. Brady(5), Nancy Bartolotti(5), Aashutosh Shetti(4), Jacqueline A. Bonds(4), Robert A. Marr(4), A Solomon(4), Gustavo Pigino(4), Željka Korade(3), Károly Mirnics(3), Otto Rapalino(3), Ahmed Disouky(3), Daniel A. Peterson(3), Yuan‐Shih Hu(3), Archana Gadadhar(3)