Bret Duffin

Morgridge Institute for Research — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index650citations13works0.02yr avg
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Research Topics

Pluripotent Stem Cells Research(7), CRISPR and Genetic Engineering(4), Single-cell and spatial transcriptomics(4), Liver physiology and pathology(3), Cancer Genomics and Diagnostics(2)

Publications13 total

Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing
Stem Cell Reports·2023· 17 citedOpen Access
Generation of anti-GD2 CAR macrophages from human pluripotent stem cells for cancer immunotherapies
Stem Cell Reports·2023· 76 citedOpen Access
Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro
Genomics·2022· 9 citedOpen Access
Reproducibility across single-cell RNA-seq protocols for spatial ordering analysis
PLoS ONE·2020· 7 citedOpen Access
Rapid changes in chromatin structure during dedifferentiation of primary hepatocyte <i>s in vitro</i>
2020· 1 citedOpen Access
Co-culture with mouse embryonic fibroblasts improves maintenance of metabolic function of human small hepatocyte progenitor cells
Current Research in Toxicology·2020· 7 citedOpen Access
Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics
PLoS Computational Biology·2019· 11 citedOpen Access
Reproducibility across single-cell RNA-seq protocols for spatial ordering analysis
2019Open Access
A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia
Stem Cell Reports·2019· 32 citedOpen Access
Species-specific developmental timing is maintained by pluripotent stem cells ex utero
Developmental Biology·2017· 58 cited
Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts
Stem Cell Reports·2015· 101 citedOpen Access
EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments
Bioinformatics·2015· 92 citedOpen Access
Nonirradiated NOD,B6.SCID Il2rγ−/− KitW41/W41 (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells
Stem Cell Reports·2015· 239 citedOpen Access

Frequent Co-authors

James A. Thomson(13), Ron Stewart(10), Brian E. McIntosh(7), Scott Swanson(7), Jennifer M. Bolin(7), Li‐Fang Chu(5), Morten Seirup(5), Srikumar Sengupta(5), Ning Leng(4), Christina Kendziorski(4), Rhonda Bacher(4), Matthew E. Brown(3), John Steill(3), Angela L. Elwell(3), Cara Argus(3), John P. Maufort(2), Igor I. Slukvin(2), Jue Zhang(2), Sarah Webster(2), Christopher Barry(2)