Astrid Magenau

Garvan Institute of Medical Research — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index3.8kcitations65works4.02yr avg
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Research Topics

Advanced Fluorescence Microscopy Techniques(11), Lipid Membrane Structure and Behavior(10), Cancer Cells and Metastasis(9), Cellular Mechanics and Interactions(8), 3D Printing in Biomedical Research(7)

Publications65 total

ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion
2025Open Access
Genomic and outcome analysis of recurrent versus de novo metastatic pancreatic ductal adenocarcinoma (PDAC) receiving systemic therapy: Results from the Australian MoST and CaSP screening programs.
Journal of Clinical Oncology·2025
Targeting the NPY/NPY1R signaling axis in mutant p53–dependent pancreatic cancer impairs metastasis
Science Advances·2025· 5 citedOpen Access
1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)
Annals of Oncology·2024Open Access
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response
Science Advances·2024· 15 citedOpen Access
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
Science Advances·2023· 8 citedOpen Access
Cell-derived Matrix Assays to Assess Extracellular Matrix Architecture and Track Cell Movement
BIO-PROTOCOL·2022· 7 citedOpen Access
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
Science Advances·2021· 44 citedOpen Access
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
Cell Reports·2021· 71 citedOpen Access
Single Cell Transcriptomics Reveals Involution Mimicry During the Specification of the Basal Breast Cancer Subtype
SSRN Electronic Journal·2020· 1 citedOpen Access
Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
2019· 10 citedOpen Access
ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling
Nature Communications·2018· 56 citedOpen Access
Removing physiological motion from intravital and clinical functional imaging data
eLife·2018· 45 citedOpen Access
Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer
Cell Reports·2018· 71 citedOpen Access
Author response: Removing physiological motion from intravital and clinical functional imaging data
2018Open Access
Unmixing spectrally overlapping FRET biosensors in vivo using multispectral FLIM (Conference Presentation)
2018
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts
Cell Reports·2017· 90 citedOpen Access
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
Science Translational Medicine·2017· 263 citedOpen Access
Abstract PR07: A biosensor mouse to predict the dissociation and spread of pancreatic cancer
Cancer Research·2017· 1 cited
Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI
Scientific Reports·2016· 17 citedOpen Access
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Frequent Co-authors

Katharina Gaus(31), Paul Timpson(18), David Herrmann(14), J. Justin Gooding(13), Dylan M. Owen(12), James R. W. Conway(11), Jennifer P. Morton(11), Max Nobis(10), David J. Williamson(9), Claire Vennin(9), Kendelle J. Murphy(9), Sean Warren(8), David Gallego‐Ortega(7), Owen J. Sansom(7), Thomas R. Cox(7), Anaiis Zaratzian(6), Christopher J. Ormandy(6), Marina Pajic(6), Morghan C. Lucas(5), Pauline Mélénec(5)