Neil M. O’Brien‐Simpson

University of Melbourne — Australia

Dentistry · Health Sciences

57h-index10.8kcitations204works9.42yr avg
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Research Topics

Oral microbiology and periodontitis research(64), Antimicrobial Peptides and Activities(52), Chemical Synthesis and Analysis(22), Immune Response and Inflammation(21), Streptococcal Infections and Treatments(18)

Publications204 total

Membrane Selectivity of Star-Shaped Peptides: A Comparative Molecular Dynamics Study across Different Bacterial and Mammalian Bilayers
The Journal of Physical Chemistry B·2025
Developing a Gram-Negative Selective Peptide–Drug Conjugate
ACS Omega·2025Open Access
Microfluidics enables rapid and facile fabrication of multi-component antimicrobial nanoparticles
Chemical Engineering Journal·2025· 1 citedOpen Access
Novel action of proline-rich antimicrobial peptides Api88, Api137, Onc72 and Onc112 against <i>Pseudomonas aeruginosa</i> and <i>Escherichia coli</i> in ion-rich environments
2025
Lipidated SNAPP-Stars Target and Kill Multidrug-Resistant Bacteria within Minutes
ACS Applied Materials & Interfaces·2025· 2 cited
Multi-disciplinary approaches paving the way for clinically effective peptide vaccines for cancer
npj Vaccines·2025· 13 citedOpen Access
Non‐Anticoagulant Heparin: An In Vitro Investigation of a Novel Therapeutic Approach for Oral Cancer
Oral Diseases·2025Open Access
Author response for "Non‐Anticoagulant Heparin: An In Vitro Investigation of a Novel Therapeutic Approach for Oral Cancer"
2025
Author response for "Non‐Anticoagulant Heparin: An In Vitro Investigation of a Novel Therapeutic Approach for Oral Cancer"
2024
One-Step Synthesis of Antimicrobial Polypeptide-Selenium Nanoparticles Exhibiting Broad-Spectrum Efficacy against Bacteria and Fungi with Superior Resistance Prevention
ACS Applied Materials & Interfaces·2024· 10 cited
Non-anticoagulant heparin exerts selective anticancer effects in oral squamous cell carcinoma cells in vitro
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology·2024
Dimerization and lysine substitution of melittin have differing effects on bacteria
Frontiers in Pharmacology·2024· 4 citedOpen Access
3D printed and smart alginate wound dressings with pH-responsive drug and nanoparticle release
Chemical Engineering Journal·2024· 48 citedOpen Access
Synthetic peptide branched polymers for antibacterial and biomedical applications
Nature Reviews Bioengineering·2024· 53 cited
Real-time, label-free detection and identification of bacteria through non-invasive optical imaging
Microbes and Infection·2023· 6 citedOpen Access
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum
Analytica Chimica Acta·2023· 40 citedOpen Access
Inside Back Cover: The effect of tailing lipidation on the bioactivity of antimicrobial peptides and their aggregation tendency
Aggregate·2023· 2 citedOpen Access
Directed chemical dimerisation enhances the antibacterial activity of the antimicrobial peptide MSI-78(4–20)
Australian Journal of Chemistry·2023· 4 citedOpen Access
One step antimicrobial coatings for medical device applications based on low fouling polymers containing selenium nanoparticles
Chemical Engineering Journal·2023· 34 cited
Effect of a protease‐activated receptor‐2 antagonist (<scp>GB88</scp>) on inflammation‐related loss of alveolar bone in periodontal disease
Journal of Periodontal Research·2023· 4 citedOpen Access
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Frequent Co-authors

Eric C. Reynolds(38), Stuart G. Dashper(11), James A. Holden(10), Paul D. Veith(9), Jason C. Lenzo(7), Andrea J. O’Connor(6), Rishi D. Pathirana(6), Nada Slakeski(5), Greg G. Qiao(4), Wenyi Li(4), Jessica D. Cecil(4), Katrina A. Walsh(4), Rita Paolini(4), Brigitte Hoffmann(4), Shu Jie Lam(3), Namfon Pantarat(3), Frances Separovic(3), John D. Wade(3), Dina Chen(3), Tao Huang(3)