John Stagg

Centre Hospitalier de l’Université de Montréal — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index18.7kcitations269works1.82yr avg
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Research Topics

Adenosine and Purinergic Signaling(150), Cancer Immunotherapy and Biomarkers(120), Immune Cell Function and Interaction(45), Peptidase Inhibition and Analysis(43), Immunotherapy and Immune Responses(35)

Publications267 total

Supplementary Tables and Figures from CD73 Inhibits cGAS–STING and Cooperates with CD39 to Promote Pancreatic Cancer
2025Open Access
Neoadjuvant immune-modulating SBRT and anti-CD73 to increase response to anti-PD-L1 and chemotherapy in early ER+/HER2- breast cancer: primary endpoint and translational results from the randomized Neo-CheckRay trial
2025Open Access
Distributed Biomarker Discovery for Immuno-Oncology
2025Open Access
Abstract B044: Distributed Transcriptomic Modeling for Biomarker Discovery in Immuno-Oncology
Clinical Cancer Research·2025
Abstract 6157: PAR2 inhibitors reduce resistance to immunotherapy against cancer
Cancer Research·2025
ATP released by ultrasound targeted microbubble cavitation induces vascular inflammation and improves immune checkpoint blockade efficacy
Theranostics·2025· 1 citedOpen Access
Low-dose Buprenorphine for Pain in a Pregnant Patient With Sickle Cell Disease
Journal of Pain and Symptom Management·2025
The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
Cell Reports·2025· 3 citedOpen Access
Data from Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T-cell Pyrimidine Synthesis
2025· 1 citedOpen Access
Supplementary Data from Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T-cell Pyrimidine Synthesis
2025Open Access
Supplementary Data from Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T-cell Pyrimidine Synthesis
2025Open Access
Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T-cell Pyrimidine Synthesis
Cancer Research·2024· 10 cited
2O TILs and PD-L1 early dynamics in the randomized Neo-CheckRay phase II trial evaluating neo-adjuvant immuno-radiation and adenosine pathway blockade for early-stage, high risk ER+/HER2- breast cancer (BC)
Immuno-Oncology Technology·2024· 1 citedOpen Access
525 Adenosine uptake through equilibrative nucleoside transporter-1 suppresses antitumor immunity by pyrimidine starvation
Regular and Young Investigator Award Abstracts·2024Open Access
Targeting G Protein–Coupled Receptors in Immuno-Oncological Therapies
The Annual Review of Pharmacology and Toxicology·2024· 8 citedOpen Access
Spatially mapping the single-cell immune landscapes of melanoma brain metastases using imaging mass cytometry.
Journal of Clinical Oncology·2024
The long and winding road to biomarkers for immunotherapy: a retrospective analysis of samples from patients with triple-negative breast cancer treated with pembrolizumab
ESMO Open·2024· 8 citedOpen Access
Abstract 684: DT-9045, a novel PAR2 inhibitor with best-in-class properties that reduces resistance to both EGFR-targeting therapies and immunotherapy in oncology models
Cancer Research·2024
Author Correction: Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial
Nature Communications·2023· 1 citedOpen Access
19P The prognostic value of soluble CD73 in advanced triple-negative breast cancer: An exploratory analysis of the SYNERGY trial
Immuno-Oncology Technology·2023Open Access
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Frequent Co-authors

Mark J. Smyth(18), Bertrand Allard(16), Sandra Pommey(11), Sherene Loi(9), David Allard(8), Phillip K. Darcy(8), Paul A. Beavis(7), Laurence Buisseret(6), Upulie Divisekera(5), Jacques Galipeau(5), Martin Turcotte(5), Benjamin Haibe‐Kains(4), Deepak Mittal(4), Christos Sotiriou(4), Lorenzo Galluzzi(3), Patrizia Agostinis(3), Jitka Fučíková(3), Udo S. Gaipl(3), Abhishek D. Garg(3), Akseli Hemminki(3)